7620-28-2Relevant articles and documents
Preparation method of beta-homoglutamic acid
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Paragraph 0022; 0033-0034, (2020/11/05)
The invention belongs to the field of preparation of organic compounds, and provides a preparation method of beta-homoglutamic acid. The method is characterized in that: 3-cyclohexenecarboxylic acid is used as a raw material, beta-homoglutamic acid is synthesized at a high yield through three the steps of reactions of Curtius rearrangement, olefin oxidation and protection group removal, and beta-homoglutamic acid with high yield and high optical purity can be obtained through configuration retention by using optically pure 3-cyclohexenecarboxylic acid. The method has the advantages of easily available raw materials, mild reaction conditions and low cost, and is suitable for large-scale preparation of beta-homoglutamic acid.
VITAMIN COMPRISING PYROLOQUINOLINE QUINONE AND USE THEREOF
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Page/Page column 20, (2008/06/13)
It is an object of the present invention to clarify the biochemical role of pyrroloquinoline quinone (PQQ) in living bodies by identifying an enzyme that uses PQQ as a coenzyme in mammals and then by clarifying the oxidation-reduction reaction, with which PQQ is associated as a coenzyme in living bodies. The present invention provides a method of using pyrroloquinoline quinone as a coenzyme for 2-aminoadipate 6-semialdehyde dehydrogenase.
TOTAL SYNTHESIS OF ENANTIOMERICALLY PURE D-α-AMINOADIPIC ACID
Amoroso, Rosa,Cardillo, Giuliana,Romero, Marta Susana,Tomasini, Claudia
, p. 75 - 78 (2007/10/02)
The diastereoselective cyclization of amidal (S,R)-2a, promoted by Hg(OTFA)2, afforded the imidazolidin-4-one (1'S,2R,5R)-3a as a single diastereoisomer. The subsequent transformation of the carbon-mercury bond and the acid hydrolysis of the heterocycle gave enantiomerically pure D-α-aminoadipic acid.