72019-91-1

Basic information

• Product Name: 1-CHLORO-6-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE
• Synonyms: 1-CHLORO-6-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE;1-CHLORO-6-METHOXY-3,4-DIHYDRONAPHTHALENE-2-CARBOXALDEHYDE;1-chloro-6-methoxy-3,4-dihydro-2-naphthalenecarbaldehyde
• CAS NO: 72019-91-1
• Molecular Formula: C₁₂H₁₁ClO₂
• Molecular Weight: 222.67
• Mol File: 72019-91-1.mol

Chemical Properties

• Melting Point: 91 °C
• Boiling Point: 356.3±42.0 °C(Predicted)
• Appearance: /
• Density: 1.25±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 1-CHLORO-6-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CHLORO-6-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE(72019-91-1)
• EPA Substance Registry System: 1-CHLORO-6-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE(72019-91-1)

Safety Data

• Hazardous Substances Data: 72019-91-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1-CHLORO-6-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE is used as a versatile intermediate for the synthesis of a wide range of organic compounds due to its unique structure and reactivity.
Used in Medicinal Chemistry:
1-CHLORO-6-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE is used as a potential target for drug discovery research, given its potential biological activities and the presence of functional groups that can be exploited for the development of new pharmaceutical agents.
Used in Pharmaceutical Industry:
1-CHLORO-6-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE is used as a key building block in the design and synthesis of novel drug candidates, leveraging its chemical properties to create molecules with therapeutic potential.
Used in Chemical Research:
1-CHLORO-6-METHOXY-3,4-DIHDRO-NAPHTHALENE-2-CARBALDEHYDE is used as a subject of study in chemical research to explore its reactivity, properties, and potential applications in various chemical processes and reactions.

Upstream product

• 108-24-7 acetic anhydride 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 14707-26-7 4,5-Dihydro-7-methoxy-1H-benzindazol 
• 668418-98-2 C₁₈H₁₆ClNO₂ 
• 1619237-28-3 (E)-6-methoxy-2-(((4-nitrophenyl)imino)methyl)-3,4-dihydronaphthalen-1-ol 
• 14784-05-5 8-methoxy-2-phenyl-5,6-dihydrobenzo[h]quinazoline 
• 1297610-98-0 1-phenyl-3,4-dihydro-6-methoxynaphthalene-2-carbaldehyde 
• 78554-65-1 7-methoxy-4,5-dihydronaphtho<1,2-b>thiophene-2-carboxylic acid 
• 1219628-81-5 6-methoxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenoxy)-3,4-dihydronaphthalene-2-carbaldehyde 
• 97135-18-7 (+/-)-trans-10,11-dihydroxy-10,11-dihydrodibenzyacridine 
• 78167-93-8 3,4-dihydro-3,4-dihydroxybenzacridine 
• 57595-75-2 7-methoxy-2-phenyl-4,5-dihydro-2H-benzo[g]indazole 
• 111378-92-8 {6-Methoxy-2-[(Z)-phenyliminomethyl]-3,4-dihydro-naphthalen-1-yl}-phenyl-amine; hydrochloride 
• 138911-93-0 8,10-diamino-3-methoxy-5,6-dihydrobenzopyrimido<4,5-b>quinoline 

Relevant articles and documents

SDS/Ac2O/H2O: Surfactant-mediated cleavage of imines with acetic anhydride to carbonyls and acetanilides in water

Surfactant (SDS)-mediated cleavage of imines was achieved with acetic anhydride to the corresponding carbonyls (aldehydes and ketones) and acetanilides in water at 25-30°C with very good to excellent yields, thus contributing significantly to the green chemistry concept. Copyright Taylor & Francis Group, LLC.

Selective synthesis of some 4,5-dihydro-2H-benzo[g]indazoles and 8,9-dihydro-2H-benzo[e]indazoles via the Vilsmeier-Haack reaction under thermal and microwave assisted conditions

A selective and easy method is described for the synthesis of 4,5-dihydro-2H-benzo[g]indazoles and 8,9-dihydro-2H-benzo[e]indazoles by the Vilsmeier-Haack reaction of various tetralone phenylhydrazones under thermal and microwave irradiation conditions.