72020-06-5

Basic information

• Product Name: 2-(2-isopropyl-5-methylcyclohexyloxy)tetrahydro-2H-pyran
• CAS NO: 72020-06-5
• Molecular Weight: 240.386
• Mol File: 72020-06-5.mol
• Article Data: 60

Chemical Properties

• CAS DataBase Reference: 2-(2-isopropyl-5-methylcyclohexyloxy)tetrahydro-2H-pyran(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-isopropyl-5-methylcyclohexyloxy)tetrahydro-2H-pyran(72020-06-5)
• EPA Substance Registry System: 2-(2-isopropyl-5-methylcyclohexyloxy)tetrahydro-2H-pyran(72020-06-5)

Safety Data

• Hazardous Substances Data: 72020-06-5(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 89-78-1 menthol 
• 2216-51-5 (-)-menthol 

Downstream Products

• 16052-42-9 (1R,2S,5R)-menthyl chloride 
• 13371-12-5 neomenthyl chloride 
• 5113-93-9 (1R)-trans-p-menth-2-ene 
• 87161-57-7 (1S,2S,4R)-2-bromo-1-isopropyl-4-methylcyclohexane 
• 1198-91-0 p-menthan-3-one oxime 
• 2230-89-9 menthyl formate 
• 89-48-5 2-isopropyl-5-methylcyclohexyl acetate 
• 10458-14-7 Menthone 
• 61949-23-3 menthyl formate 
• 2623-23-6 L-menthyl acetate 
• 10458-14-7 (2R,5S)-menthone 
• 89-78-1 menthol 
• 2216-51-5 (-)-menthol 
• 112570-37-3 5-(2-Isopropyl-5-methyl-cyclohexyloxy)-5-phenylsulfanyl-pentan-1-ol 

Relevant articles and documents

Copper-Catalyzed Oxidative Acetalization of Boronic Esters: An Umpolung Strategy for Cyclic Acetal Synthesis

A protocol for the acetalization of boronic esters is described. The reaction is catalyzed by copper, and the conditions proved to be mild and were amenable to a variety of functional groups. We expanded the Chan-Lam coupling to include C(sp3) nucleophiles and converted them into corresponding acetals. This method allows for the orthogonal acetalization of substrates with reactive, acid-sensitive functional groups.

Magnetic Fe3O4@silica sulfuric acid nanoparticles promoted regioselective protection/deprotection of alcohols with dihydropyran under solvent-free conditions

Protection (and deprotection) of hydroxyl groups via tetrahydropyranylation was carried out effectively using a catalytic amount of Fe3O4 supported silica sulphuric acid nanoparticles (Fe3O4@SiO2@SO3H) under solvent-free conditions. The synthesized nanocatalyst was characterized by XRD, TEM, FT-IR etc. A wide range of tetrahydropyranylated alcohol derivatives were synthesized using this heterogeneous magnetic nanocatalyst within 10-20 min with high yields. In addition, tetrahydropyranyl ethers could also be deprotected to the parent alcoholic compounds in the presence of MeOH using the same catalyst. After completion of the reactions, the catalyst was easily separated from the reaction medium using an external magnet, which ameliorated the overall synthetic process. The catalyst was recovered and reused for five successive reactions without any appreciable loss in its activity. Mild reactions conditions, operational simplicity, solvent free conditions, high selectivity, easy recyclability of the magnetic nanocatalyst, and high yields can be considered as the advantageous features of our procedure.

Supported N-propylsulfamic acid onto Fe3O4 magnetic nanoparticles as a reusable and efficient nanocatalyst for the protection/deprotection of hydroxyl groups and protection of aldehydes

N-propylsulfamic acid supported onto Fe3O4 magnetic nanoparticles (MNPs-PSA) as an efficient and magnetically reusable nanocatalyst has been reported for the tetrahydropyranylation/depyranylation of a wide variety of alcohols and phenols by changing the solvent medium. Also, the protection of aldehydes as acylals using Ac2O in the presence of catalytic amount MNPs-PSA in good to high yields at room temperature under solvent-free conditions is described. After completing the reaction, the catalyst was easily separated from the reaction mixture with the assistance of an external magnetic field and reused for several consecutive runs without significant loss of their catalytic efficiency.