72046-68-5

Basic information

• Product Name: Benzene, 1,1'-methylenebis[2,4-dimethoxy-
• CAS NO: 72046-68-5
• Molecular Formula: C17H20O4
• Molecular Weight: 288.343
• Mol File: 72046-68-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-methylenebis[2,4-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-methylenebis[2,4-dimethoxy-(72046-68-5)
• EPA Substance Registry System: Benzene, 1,1'-methylenebis[2,4-dimethoxy-(72046-68-5)

Safety Data

• Hazardous Substances Data: 72046-68-5(Hazardous Substances Data)

Upstream product

• 7314-44-5 2,4-dimethoxylbenzyl alcohol 
• 75-52-5 nitromethane 
• 151-10-0 1,3-Dimethoxybenzene 
• 107-15-3 ethylenediamine 
• 465498-58-2 2,2-di-2,4-di-methoxyphenyl-1,3-indanedione 
• 50-00-0 formaldehyd 
• 7664-93-9 sulfuric acid 

Relevant articles and documents

Sc(OTf)3-Catalyzed Synthesis of Symmetrical Dithioacetals and Bisarylmethanes Using Nitromethane as a Methylene Source

Use of nitromethane as an electrophilic methylene source for the synthesis of symmetrical dithioacetals and bisarylmethanes has been showcased using Sc(OTf)3 as a catalyst. The procedure allows straightforward access to the densely functionalized dithioacetals and bisarylmethanes under mild conditions. Additionally, the method has been applied for the synthesis of antimalarial tetramethyl mellotojaponin C and anticancer dimeric phloroglucinol derivative.

The role of aromatic radical cations and benzylic cations in the 2,4,6-triphenylpyrylium tetrafluoroborate photosensitized oxidation of ring-methoxylated benzyl alcohols in CH2Cl2 solution

A steady-state and laser flash photolysis (LFP) study of the TPPBF 4-photosensitized oxidation of ring-methoxylated benzyl alcohols has been carried out. Direct evidence on the involvement of intermediate benzyl alcohol radical cations and benzylic cations in these reactions has been provided through LFP experiments. The reactions lead to the formation of products (benzaldehydes, dibenzyl ethers, and diphenylmethanes) whose amounts and distributions are influenced by the number and relative position of the methoxy substituents. This behavior has been rationalized in terms of the interplay between the stabilities of benzyl alcohol radical cations and benzyl cations involved in these processes. A general mechanism for the TPPBF 4-photosensitized reactions of ring-methoxylated benzyl alcohols has been proposed, where the a-OH group of the parent substrate acts as the deprotonating base promoting α-C-H deprotonation of the benzyl alcohol radical cation (formed after electron transfer from the benzyl alcohol to TPP*) to give a benzyl radical and a protonated benzyl alcohol, precursor of the benzylic cation. This hypothesis is in contrast with previous studies, where formation of the benzyl cation was suggested to occur from the neutral benzyl alcohol through the Lewis acid action of excited TPP+ (TPP*).