72085-01-9 Usage
Uses
Used in Topical Pain Relief Applications:
Benzocaine is utilized as a local anesthetic in topical pain relief products for its capacity to numb the skin and alleviate discomfort caused by conditions such as sunburn, insect bites, and minor cuts. Its effectiveness in these applications stems from its ability to interfere with nerve signal transmission, thus reducing the sensation of pain.
Used in Over-the-Counter Medications:
Benzocaine is found in a variety of over-the-counter topical formulations, including creams, gels, and sprays, due to its accessibility and efficacy in providing quick relief from minor skin irritations and injuries. Its presence in these products underscores its widespread use and acceptance for managing temporary pain and itching.
Used in Cautionary Applications:
While benzocaine is beneficial for localized pain and itching relief, it is also used with caution due to the potential for serious health risks associated with excessive application or ingestion. These risks include allergic reactions and methemoglobinemia, a condition that, while rare, can be life-threatening. As such, benzocaine serves as a reminder of the importance of following recommended guidelines for use to ensure safety and effectiveness.
Check Digit Verification of cas no
The CAS Registry Mumber 72085-01-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,0,8 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 72085-01:
(7*7)+(6*2)+(5*0)+(4*8)+(3*5)+(2*0)+(1*1)=109
109 % 10 = 9
So 72085-01-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N2O3/c14-7-6-12-10(15)8-13-11(16)9-4-2-1-3-5-9/h1-5,14H,6-8H2,(H,12,15)(H,13,16)
72085-01-9Relevant academic research and scientific papers
Catalyst and solvent-free amidation of inactive esters of N-protected amino acids
Nadimpally, Krishna Chaitanya,Thalluri, Kishore,Palakurthy, Nani Babu,Saha, Abhijit,Mandal, Bhubaneswar
supporting information; experimental part, p. 2579 - 2582 (2011/06/21)
A catalyst free procedure for the preparation of amides from inactive esters of N-protected amino acids and various amines is demonstrated under mild reaction conditions. Our effort to recover excess amine and generated alcohol is an approach towards environment friendly and cost effective synthesis under easy operational conditions.
O-ACYLATION OF 2-(DIMETHYLAMINO)-1-ETHANOL BY p-NITROPHENYL ESTERS OF N-SUBSTITUTED AMINO ACID
Topuzyan, V. O.,Alebyan, G. P.,Mndzhoyan, O. L.
, p. 733 - 737 (2007/10/02)
The kinetics of the O-acylation of 2-(dimethylamino)-1-ethanol by the p-nitrophenyl ester of N-(benzyloxycarbonyl)amino acids and also benzoylaminoacetic, acetic, and chloroacetic acids were studied.The rate constants of the pseudofirst-order reaction wer
