7209-12-3

Usage

Uses

Used in Organic Synthesis:
1-(4,5-DIBROMO-2-THIENYL)-1-ETHANONE is used as a building block in organic synthesis for the creation of more complex molecules. Its unique structure and reactivity make it a valuable component in the development of advanced chemical compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-(4,5-DIBROMO-2-THIENYL)-1-ETHANONE serves as a key intermediate in the synthesis of various drugs and medicinal compounds. Its incorporation into these molecules can potentially enhance their therapeutic properties and effectiveness in treating specific health conditions.

Upstream product

• 3140-93-0 2,3-dibromothiophen 
• 75-36-5 acetyl chloride 
• 88-15-3 2-Acetylthiophene 
• 3141-24-0 2,3,5-tribromothiophene 
• 64-19-7 acetic acid 

Downstream Products

• 7209-11-2 2-acetyl-4-bromothiopene 
• 6324-10-3 4,5-Dibromo-thiophene-2-carboxylic acid 
• 16694-18-1 4-bromo-thiophene-2-carboxylic acid 
• 1435464-42-8 1-[4,5-bis(2,5-dimethylthiophen-3-yl)thiophen-2-yl]-3-phenylpropane-1,3-dione 
• 1435464-54-2 diphenylboryl{1,3-bis[4,5-bis(2,5-dimethylthien-3-yl)thiophen-2-yl]propane-1,3-dionate} 
• 1435464-53-1 diphenylboryl{1-[4,5-bis(2,5-dimethylthiophen-3-yl)thiophen-2-yl]-3-(thiophen-2-yl)propane-1,3-dionate} 
• 1435464-52-0 diphenylboryl{1-[4,5-bis(2,5-dimethylthiophen-3-yl)thiophen-2-yl]-3-phenyl-propane-1,3-dionate} 
• 1435464-49-5 bis(pentafluorophenyl)boryl{1-[4,5-bis(2,5-dimethylthiophen-3-yl)thiophen-2-yl]-3-phenylpropane-1,3-dionate} 
• 1435464-48-4 bis(pentafluorophenyl)boryl{1-[4,5-bis(2,5-dimethylthiophen-3-yl)thiophen-2-yl]-3-phenylpropane-1,3-dionate} 
• 1435464-45-1 difluoroboryl{1-[4,5-bis(2,5-dimethylthiophen-3-yl)thiophen-2-yl]-3-phenyl-propane-1,3-dionate} 

Relevant academic research and scientific papers

A convenient and efficient preparation of 2-acetyl-4,5-difluorothiophene

A convenient, five-step preparation of 2-acetyl-4,5-difluorothiophene from 2,3-dibromothiophene is described. Copyright Taylor & Francis Group, LLC.

Five-membered heterocyclic oxo carboxylic acid compound and medical application thereof

The invention relates to a five-membered heterocyclic oxo carboxylic acid compound and a medical application thereof. Specifically, the invention relates to a compound, a pharmaceutical salt, a prodrug, a hydrate, a solvate or a crystal form as shown in a formula (I), and also relates to a preparation method of the compound, a pharmaceutical composition containing the compound and an application of the pharmaceutical composition as a secretion regulator of interferon type I, especially as an STING agonist in preparation of medicines for preventing and/or treating I-type interferon related diseases.

Densely packed open microspheres by soft template electropolymerization of benzotrithiophene-based monomers

Here, a soft electropolymerization approach (called templateless) is used to prepare extremely ordered porous surface structures. For the first time, benzotrithiophene-based monomers are chosen for their high aromaticity and exceptional electropolymerizat

Pyrazoles: 'one-pot' synthesis from arenes and carboxylic acids

A rapid and efficient method for 'one-pot' synthesis of pyrazoles from (hetero)arenes and carboxylic acids via successive formation of ketones and β-diketones followed by heterocyclization with hydrazine has been developed. The utility of the RCOOH/TfOH/TFAA acylation system for intermediate production of ketones and 1,3-diketones is a key feature of this approach. The preliminary evaluation of the anticancer activity of the synthesized pyrazoles is performed.

Bromothiophene Reactions. I. Friedel-Crafts Acylation

Friedel-Crafts acylation of 2,5-dibromo- and 2,3,5-tribromothiophenes with different acyl chlorides and anhydrous aluminium trichloride has been studied.The reaction afforded a mixture of acyl derivatives and tetrabromothiophene.The results obtained suggest a mechanism which involves the formation of bromine cations in the reaction medium.Several products obtained in this reaction are described.