72102-89-7

Usage

Type of compound

Aldehyde

Substitution

Phenoxy group substituted with two methyl groups

Usage

Intermediate in the synthesis of pharmaceuticals and organic compounds, flavoring agent in the food industry, fragrances and perfumes, potential building block in the production of organic chemicals and materials

Known for

Distinctive aroma

InChI:InChI=1/C10H12O2/c1-8-4-3-5-9(2)10(8)12-7-6-11/h3-6H,7H2,1-2H3

Upstream product

• 6279-47-6 ethyl 2-(2,6-dimethylphenoxy)acetate 
• 129308-02-7 1-(2,2-diethoxyethoxy)-2,6-dimethylbenzene 
• 576-26-1 2.6-dimethylphenol 
• 16737-71-6 2-(2,6-dimethylphenoxy)ethanol 
• 15261-41-3 1-allyloxy-2,6-dimethylbenzene 

Downstream Products

• 1370283-17-2 C₁₉H₁₉N₃O₃S 
• 1370283-22-9 C₁₉H₁₉N₃O₂S₂ 
• 134671-35-5 2C₁₁H₁₆N₄O₂*H₂O₄S 

Relevant academic research and scientific papers

The synthesis of some new hydrazone derivatives containing the benzothiazole moiety

Hydrazones are an important class of compounds found in many synthetic products. Due to their importance in synthetic chemistry, the present article reports the synthesis of a new series of ten compounds based on the coupling of 2-oxo-3(2H)-benzothiazoleacetic acid, hydrazide and 2-thioxo-3(2H)- -benzothiazoleacetic acid, hydrazide with different aldehydes. The structures of the synthesized compounds were confirmed by elemental analyses, IR, 1H- -NMR, 13C-NMR and FAB+-MS spectral data. Copyright 2012 (CC) SCS.

SALICYLIC ACID DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THEM

The present invention provides the salicylic acid derivative compound or its pharmaceutically acceptable salt useful for treating several diseases, a pharmaceutical composition containing the compound or its salt, and a treating or preventing method using the compound or its salt. The salicylic acid derivative compound of the present invention has suppressing effect on excitatory toxicity, anti-oxidant effect, cell-protecting effect, anti-inflammatory effect, etc. and can be effectively used for treating or preventing brain neuronal disease such as amyotrophic lateral sclerosis, Parkinson' s disease, Huntington' s disease, Alzheimer' s disease, stroke, traumatic brain injury and traumatic spinal cord injury; ocular disease such as glaucoma, diabetic retinopathy and macular degeneration; pain disease such as neuropathic pain; and inflammatory disease such as arteriosclerosis, gastritis, colitis, arthritis, nephritis, hepatitis, cancer and degenerative disease.

Ozonolysis of Olefins VIII [1]. Synthesis of Phenoxyacetaldehydes by Ozonolysis of Allylphenylethers

A new route for the preparation of a series of phenoxyacetaldehydes (2a-j) which are useful intermediates or products, is described. It starts from the easily available allylphenylethers 1a-j which are ozonized at -40°C and further treated with dimethylsulfide to give solutions of the corresponding phenoxyacetaldehydes 2a-j; these are purified by column chromatography. Reaction of 2a-j with 1-methyl-1-phenylhydrazine leads to the corresponding hydrazones 3a-c, 3e-g, 3i, and 3j. The aldehydes can also be transformed into the stable dimethylcetals 4a, 4e, 4h, and 4i by reaction with trimethyl orthoformate.