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6-(ethoxycarbonyl)-3-(2-(4-chlorophenyl)thiazol-5-yl)-5-oxohexanoic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

721920-85-0

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721920-85-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 721920-85-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,2,1,9,2 and 0 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 721920-85:
(8*7)+(7*2)+(6*1)+(5*9)+(4*2)+(3*0)+(2*8)+(1*5)=150
150 % 10 = 0
So 721920-85-0 is a valid CAS Registry Number.

721920-85-0Relevant academic research and scientific papers

Synthesis of pyrazoles and isoxazoles as potent αvβ3 receptor antagonists

Penning, Thomas D.,Khilevich, Albert,Chen, Barbara B.,Russell, Mark A.,Boys, Mark L.,Wang, Yaping,Duffin, Tiffany,Engleman, V. Wayne,Finn, Mary Beth,Freeman, Sandra K.,Hanneke, Melanie L.,Keene, Jeffery L.,Klover, Jon A.,Nickols, G. Allen,Nickols, Maureen A.,Rader, Randall K.,Settle, Steven L.,Shannon, Kristen E.,Steininger, Christina N.,Westlin, Marisa M.,Westlin, William F.

, p. 3156 - 3161 (2007/10/03)

We describe a series of pyrazole and isoxazole analogs as antagonists of the αvβ3 receptor. Compounds showed low to sub-nanomolar potency against αvβ3, as well as good selectivity against αIIbβ3

PYRAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES

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Page 38, (2010/02/07)

The present invention relates to pharmaceutical compositions comprising compounds of the Formula (I), and methods of selectively inhibiting or antagonizing the αVβ3 and/or the α Vβ5 integrin without significantly inhibitin

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