496047-46-2

Upstream product

• 496047-44-0 2-(2-benzyloxy-4-methoxybenzoyl)-3-[(1-imidazolyl)carbonyl]pyridine 
• 205640-56-8 2-benzyloxy-4-methoxyphenylmagnesium bromide 
• 164463-34-7 2-(2-benzyloxy-4-methoxybenzoyl)-3-pyridinecarboxylic acid 
• 150356-67-5 1-bromo-4-methoxy-2-(phenylmethoxy)benzene 
• 100-39-0 benzyl bromide 
• 63604-94-4 2-bromo-5-methoxyphenol 
• 540-88-5 acetic acid tert-butyl ester 
• 699-98-9 Pyridine-2,3-dicarboxylic anhydride 
• 496047-45-1 7-(2-benzyloxy-4-methoxyphenyl)-6-tert-butoxycarbonyl-7-hydroxy-5-oxocyclopenteno[1,2-b]pyridine 

Downstream Products

• 169745-61-3 7-(2-benzyloxy-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-(3,4-methylenedioxyphenyl)-5-hydroxycyclopenta-1,3-dieno[2,1-b]pyridine 
• 494841-92-8 tert-butyl (5S,6R,7R)-(+)-5-(2,3-dihydrobenzo[b]furan-6-yl)-7-(2-hydroxymethyl-4-methoxyphenyl)-2-(N-isopropylamino)-6,7-dihydro-5H-cyclopenta[b]pyridine-6-carboxylate 
• 721965-55-5 7-(2-benzyloxy-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-(2,3-dihydrobenzo[b]furan-6-yl)-5-hydroxy-5H-cyclopenta[b]pyridine 
• 496047-50-8 5-benzo[1,3]dioxol-5-yl-7-(2-benzyloxy-4-methoxy-phenyl)-5H-[1]pyrindine-6-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

A convenient synthetic method of a 5,7-diarylcyclopenteno-[1,2-b]pyridine-6-carboxylate: A key intermediate for potent endothelin receptor antagonists

A convenient synthetic method of 4, a key intermediate for a new class of endothelin receptor antagonists, was developed. Racemic 4 was synthesized from quinolinic anhydride in 13.4% overall yield without chromatographic purification.