72204-02-5Relevant academic research and scientific papers
Design and Synthesis of Novel Chiral Dirhodium(II) Carboxylate Complexes for Asymmetric Cyclopropanation Reactions
Adly, Frady G.,Gardiner, Michael G.,Ghanem, Ashraf
, p. 3447 - 3461 (2016/03/05)
A novel approach to the design of dirhodium(II) tetracarboxylates derived from (S)-amino acid ligands is reported. The approach is founded on tailoring the steric influences of the overall catalyst structure by reducing the local symmetry of the ligand's N-heterocyclic tether. The application of the new approach has led to the uncovering of [Rh2(S-tertPTTL)4] as a new member of the dirhodium(II) family with extraordinary selectivity in cyclopropanation reactions. The stereoselectivity of [Rh2(S-tertPTTL)4] was found to be comparable to that of [Rh2(S-PTAD)4] (up to >99 % ee), with the extra benefit of being more synthetically accessible. Correlations based on X-ray structures to justify the observed enantioinduction are also discussed.
Reactions of hypervalent iodonium alkynyl triflates with azides: Generation of cyanocarbenes
Hyatt, I. F. Dempsey,Croatt, Mitchell P.
, p. 7511 - 7514 (2012/09/21)
HIAT me, baby, one more time: Cyanocarbenes have been formed by the reaction of azides with hypervalent iodonium alkynyl triflates (HIATs). Experimental evidence supports the potential intermediacy of an azide-substituted vinylidene or alkynyl azide, both of which could form a cyanocarbene. Trapping of the vinylidene and cyanocarbene includes O-H insertion, dimethyl sulfoxide coordination, and cyclopropanation reactions. Copyright
A new stereoselective synthesis of cyclopropanes containing quaternary stereocentres via organocatalytic michael addition to vinyl selenones
Marini, Francesca,Sternativo, Silvia,Del Verme, Francesca,Testaferri, Lorenzo,Tiecco, Marcello
experimental part, p. 1801 - 1806 (2011/02/25)
A novel organocatalytic method for the stereoselective synthesis of highly substituted cyclopropanes is reported. The Michael adducts, generated through the addition of α-substituted cyanoacetates to easily accessible vinyl selenones catalyzed by a bifunc
Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides
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, (2008/06/13)
Compounds with fungicidal and insecticidal properties having formula STR1 wherein X is N or CH; Z is O, S or NR8 ; A is hydrogen, halo, cyano, (C1 -C12)alkyl, or (C1 -C12)alkoxy; R1 and R8 are independently hydrogen or (C1 -C4)alkyl; R2 is hydrogen, (C1 -C12)alkyl, halo(C1 -C12)alkyl, (C3 -C7)cycloalkyl, halo(C3 -C7)cycloalkyl, (C2 -C8)alkenyl, halo(C2 -C8)alkenyl, (C2 -C8)alkynyl, halo(C2 -C8)alkynyl, aryl, aralkyl, heterocyclic, heterocyclic(C1 -C4)alkyl or C(R10)=N--OR9 ; R3 is hydrogen, (C1 -C12)alkyl, halo(C1 -C12)alkyl, (C3 -C7)cycloalkyl, halo(C3 -C7)cycloalkyl, (C2 -C8)alkenyl, halo(C2 -C8)alkenyl, (C2 -C8)alkynyl, halo(C2 -C8)alkynyl, aryl, aralkyl, aryl(C3 -C7)cycloalkyl, heterocyclic or heterocyclic(C1 -C4)alkyl; R4 and R5 are independently hydrogen, (C1 -C12)alkyl, halo(C1 -C12)alkyl, (C3 -C7)cycloalkyl, halo(C3 -C7)cycloalkyl, (C2 -C8)alkenyl, halo(C2 -C8)alkenyl, (C2 -C8)alkynyl, halo(C2 -C8)alkynyl, halo, cyano, (C1 -C4)alkoxycarbonyl, aryl, aralkyl, aryl(C3 -C7)cycloalkyl, heterocyclic or heterocyclic(C1 -C4)alkyl; R6 is hydrogen, (C1 -C12)alkyl, halo(C1 -C12)alkyl, (C3 -C7)cycloalkyl, halo(C3 -C7)cycloalkyl, (C2 -C8)alkenyl, halo(C2 -C8)alkenyl, (C2 -C8)alkynyl, halo(C2 -C8)alkynyl, halo, cyano, (C1 -C4)alkoxycarbonyl, aryl, aralkyl, aryl(C3 -C7)cycloalkyl, heterocyclic or heterocyclic(C1 -C4)alkyl; R7 is aryl, aralkyl, heterocyclic or heterocyclic(C1 -C4)alkyl; R9 is hydrogen, (C1 -C12,)alkyl, halo(C1 -C12)alkyl, (C2 -C8)alkenyl, halo(C2 -C8)alkenyl, (C2 -C8)alkynyl, halo(C2 -C8)alkynyl, (C1 -C4)alkylcarbonyl, (C1 -C4)alkoxycarbonyl, aryl, or aralkyl; and R10 is hydrogen, (C1 -C12)alkyl, halo(C1 -C12)alkyl, (C3 -C7)cycloalkyl, halo(C3 -C7)cycloalkyl, (C2 -C8)alkenyl, halo(C2 -C8)alkenyl, (C2 -C8)alkynyl, halo(C2 -C8)alkynyl, aryl, aralkyl, heterocyclic, or heterocyclic(C1 -C4)alkyl.
