72232-59-8Relevant academic research and scientific papers
Donor Rhodium Carbenes by Retro-Buchner Reaction
Mato, Mauro,Echavarren, Antonio M.
supporting information, p. 2088 - 2092 (2019/01/25)
Rhodium carbenes are key intermediates in a range of cycloadditions and insertion reactions. Herein, we report the first generation of donor RhII carbenes by decarbenation of 7-substituted 1,3,5-cycloheptatrienes. This discovery unlocks an improved retro-Buchner-cyclopropanation sequence, a Si?H insertion reaction for a broad-scope synthesis of allylsilanes, and a new method for the vinylogation of aldehydes. The last strategy led to the development of an iterative synthesis of E-polyenes, and to the total synthesis of navenones B and C.
Facile One Pot Thermal Dehydration and Dethioacetalization of β-Hydroxydithioacetals with Dimethyl sulphoxide: Synthesis of α,β-Unsaturated Aldehydes
Rao, Ch. Srinivasa,Chandrasekharam, M.,Patro, Balaram,Ila, Hiriyakkanavar,Junjappa, Hiriyakkanavar
, p. 5783 - 5794 (2007/10/02)
The acyclic and cyclic β-hydroxydithioacetals 3a-m and 4a-b obtained by sodium borohydride reduction (or Grignard addition) of the corresponding β-oxodithioacetals 2a-m are shown to undergo facile one pot thermal dehydration and dethioacetalization in the presence of dimethyl sulphoxide to afford the corresponding ene- and polyene aldehydes 5a-m and 6a-b in good yields.The probable mechanism of dethioacetalization with dimethyl sulphoxide has also been discussed.
Reactivity of polyvinylogation: Easy and rapid access to different polyenals
Ramondenc,Ple
, p. 10855 - 10876 (2007/10/02)
This work describes the synthesis and the reactivity of three reagents of polyvinylogation 1-3. By condensation with several aldehydes and ketones, these reagents allow the introduction of three or four doubles bonds, leading to polyenals 5-6 in one or tw
CHEMISTRY OF ENOL ETHERS. LVI. CONDENSATION OF THE ACETALS OF AROMATIC ALDEHYDES WITH 1-ETHOXY-1,3-BUTADIENE. SYNTHESIS OF ARYLPOLYENE ALDEHYDES
Makin, S. M.,Shavrygina, O. A.,Dobretsova, E. K.,Ermakova, G. A.,Dymshakova, G. M.
, p. 651 - 656 (2007/10/02)
The condensation of a series of acetals of aromatic aldehydes (benzaldehyde, 4-methoxy and 3,4-dimethoxybenzaldehyde) with 1-ethoxy-1,3-butadiene was investigated.Successful realization of the reaction requires the presence of electron-donating goups in t
