49678-07-1

Usage

Uses

Used in Fragrance and Flavor Industry:
2,4-Pentadienal, 5-(4-methoxyphenyl)-, (2E,4E)is used as a flavoring agent and fragrance ingredient for its ability to impart a sweet and spicy aroma to various products, such as perfumes, soaps, and food items.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,4-Pentadienal, 5-(4-methoxyphenyl)-, (2E,4E)is utilized for its potential medicinal properties, including antioxidant and anti-inflammatory effects, which may contribute to the development of new therapeutic agents.
Used in Pest Control:
2,4-Pentadienal, 5-(4-methoxyphenyl)-, (2E,4E)has been studied for its potential as a natural insecticide, offering an alternative to synthetic chemicals for pest control in agriculture and other applications.

Upstream product

• 24056-44-8 C₁₈H₂₈O₄ 
• 82724-67-2 1,1,5-Triethoxy-5-(4-methoxyphenyl)-2-pentene 
• 32271-54-8 (E)-1-(4-methoxyphenyl)pent-1-en-3-ol 
• 68-12-2 N,N-dimethyl-formamide 
• 18708-18-4 furfural tosylhydrazone 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 98-01-1 furfural 
• 24680-50-0 4-methoxy-trans-cinnamaldehyde 
• 15542-26-4 (2E,4E)-ethyl 5-(4'-methoxyphenyl)penta-2,4-dienoate 
• 109239-18-1 (2E,4E)-5-(4-methoxyphenyl)penta-2,4-dien-1-ol 
• 130248-53-2 (E)-4-(4-methoxyphenyl)-1-(trimethylsilyl)but-3-en-1-yne 
• 27570-08-7 4-(2-bromo-vinyl)-anisole 
• 943-89-5 (E)-3-(4-methoxyphenyl)acrylic acid 
• 201230-82-2 carbon monoxide 

Downstream Products

• 15542-37-7 (E,E)-5-(4-methoxyphenyl)-2,4-pentadienoic acid 
• 79512-92-8 ethyl 7-(4-methoxyphenyl)-2,4,6-heptatrienoate 
• 111163-35-0 (+/-)-1ξ-methoxy-13t-(4-methoxy-phenyl)-trideca-1,6t,8t,10t,12-pentaen-3-yn-5-ol 
• 267418-10-0 (4E,6E)-3-(tert-Butyl-dimethyl-silanyloxy)-7-(4-methoxy-phenyl)-2,2-dimethyl-hepta-4,6-dienoic acid ethyl ester 
• 267418-00-8 (4E,6E)-3-(tert-Butyl-dimethyl-silanyloxy)-7-(4-methoxy-phenyl)-2,2-dimethyl-hepta-4,6-dien-1-ol 
• 626254-99-7 (4E,6E)-(2S,3R)-7-(4-Methoxy-phenyl)-2-methyl-3-triethylsilanyloxy-hepta-4,6-dienoic acid methoxy-methyl-amide 
• 626254-98-6 (4E,6E)-(2S,3R)-3-Hydroxy-7-(4-methoxy-phenyl)-2-methyl-hepta-4,6-dienoic acid methoxy-methyl-amide 
• 72232-59-8 (2E,4E,6E)-7-(4-methoxyphenyl)hepta-2,4,6-trienal 
• 136795-72-7 ttt-1-(p-methoxyphenyl)-6-(p-nitrophenyl)-1,3,5-hexatriene 
• 82724-70-7 1,1,3,7-Tetraethoxy-7-(4-methoxyphenyl)-4-heptene 
• 72232-60-1 9-(4-Methoxyphenyl)-2,4,6,8-nonatetraenal 
• 106737-39-7 [5t-(4-methoxy-phenyl)-penta-2t,4-dienylidene]-malonic acid 

Relevant academic research and scientific papers

Selective Rhodium-Catalyzed Hydroformylation of Terminal Arylalkynes and Conjugated Enynes to (Poly)enals Enabled by a π-Acceptor Biphosphoramidite Ligand

The hydroformylation of terminal arylalkynes and enynes offers a straightforward synthetic route to the valuable (poly)enals. However, the hydroformylation of terminal alkynes has remained a long-standing challenge. Herein, an efficient and selective Rh-catalyzed hydroformylation of terminal arylalkynes and conjugated enynes has been achieved by using a new stable biphosphoramidite ligand with strong π-acceptor capacity, which affords various important E-(poly)enals in good yields with excellent chemo- and regioselectivity at low temperatures and low syngas pressures.

Donor Rhodium Carbenes by Retro-Buchner Reaction

Rhodium carbenes are key intermediates in a range of cycloadditions and insertion reactions. Herein, we report the first generation of donor RhII carbenes by decarbenation of 7-substituted 1,3,5-cycloheptatrienes. This discovery unlocks an improved retro-Buchner-cyclopropanation sequence, a Si?H insertion reaction for a broad-scope synthesis of allylsilanes, and a new method for the vinylogation of aldehydes. The last strategy led to the development of an iterative synthesis of E-polyenes, and to the total synthesis of navenones B and C.

Novel D-A-D based near-infrared probes for the detection of β-amyloid and Tau fibrils in Alzheimer's disease

Novel D-π-A-π-D probes were investigated for the detection of Aβ plaques and NFTs. The probes displayed remarkable optical properties, and DADNIR-2 possessed high affinity towards Tau and Aβ aggregates (Kd = 0.41 nM and 1.04 nM, respectively) with certain selectivity. DADNIR-2 could penetrate the BBB and label Aβ plaques in vivo.

Palladium-catalysed atom-economical synthesis of conjugated dienals from terminal acetylenes and acrolein

Conjugated (E,E)-dienals are versatile synthetic intermediates owing to their trifunctional, electrophilic nature and the prevalence of the (E,E)-diene in a wide range of functional molecules. It is shown herein that (E,E)-dienals can be readily prepared

Facile Preparation of α-Cyano-α,ω-Diaryloligovinylenes: A New Class of Color-Tunable Solid Emitters

An efficient Knoevenagel condensation reaction was used to construct a series of α-cyano-α,ω-diaryloligovinylenes, which show prominent fluorescence emission in the solid state. On investigating the effect of conjugation length on fluorescent properties,

Organocatalyst-mediated dehydrogenation of aldehydes to α,β-unsaturated aldehydes, and oxidative and enantioselective reaction of aldehydes and nitromethane catalyzed by diphenylprolinol silyl ether

A one-pot transformation of aldehydes into α,β-unsaturated aldehydes was developed using both N-benzyl-N-methylamine and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) as catalysts and MnO2 as a terminal oxidant. An oxidative and enantioselective reaction of aldehydes and nitromethane was established using both diphenylprolinol silyl ether and DDQ as a catalyst with MnO2 as a terminal oxidant, in which synthetically important β-substituted γ-nitro aldehydes were obtained with excellent enantioselectivity. Copyright

Palladium(II) and palladium(0)-cocatalyzed ring opening and oxidation reactions of 2-(arylmethylene)cyclopropylcarbinols

In the presence of Pd(II) acetate and triethylamine as well as triphenylphosphine, 2-(arylmethylene)cyclopropylcarbinols 1 underwent ring opening and oxidation reactions smoothly to deliver (2E,4E)-5-arylpenta-2,4-dienals 2 in toluene at 60 °C in moderate

A stereoselective synthesis of unsaturated phosphonates by Wittig-Horner reactions of bisphosphonylmethane with 5-aryl-(3-methyl)-2E,4E-pentadienals

A new type of unsaturaled phosphonates 5 were synthesized by the Wittig-Horner reactions of bisphosphonylmethane 4 with 5-aryl-2(E),4(E)-pentadienal and 5-aryl-3-methyl-2(E), 4(E)-pentadienal. The structures of all new compounds prepared were characterize

Addition of carbon nucleophiles to aldehyde tosylhydrazones of aromatic and heteroaromatic-compounds: Total synthesis of piperine and its analogs

Addition of carbon nucleophiles to aldehyde tosylhydrazones of aromatic and heteroaromatic compounds is reported. New observations have been made wherein alkylative reduction is observed in some cases whereas alkylative fragmentation is noticed in others. These findings are exploited in the synthesis of the useful alkaloid piperine and its analogs. (C) 2000 Elsevier Science Ltd.

Exclusive γ-regio functionalization of crotonaldehyde using γ-trimethylsilyl crotonaldimine. Application to the one pot synthesis of conjugated dienals

Cesium fluoride mediated reaction of γ-trimethylsilyl N-tert-butyl crotonaldimine 9 with a wide range of aldehydes takes place in DMSO at room temperature and affords exclusive γ-regio functionalized products. Heating (rt to 100°C) the δ-silyloxy imines 11 thus obtained leads, after very mild hydrolysis of the tert-butylimine function, to the conjugated dienals 14 in good yields and with excellent (E,E)-selectivities.