72254-58-1

Usage

InChI:InChI=1/C12H11N3/c1-7-12-8-4-2-3-5-9(8)15-10(12)6-11(13)14-7/h2-6,15H,1H3,(H2,13,14)

Upstream product

• 7210-27-7 2-indoleacetonitrile 
• 64-19-7 acetic acid 
• 75-05-8 acetonitrile 
• 143618-98-8 t-Boc-Trp-P-2 
• 40899-71-6 1-benzenesulfonylindole 
• 65828-74-2 (2-Indolylmethylen)-malonsaeure 
• 121897-38-9 methyl (E)-3-(1H-indol-2-yl)acrylate 
• 143618-94-4 (E)-3-(1H-indol-2-yl)acrylic acid 
• 143631-77-0 methyl 3-<2-(acetylindolyl)>-2-propenoate 
• 143618-97-7 methyl 1-methyl-5H-pyrido<4,3-b>indole-3-carboxylate 
• 65032-81-7 1-methyl-5H-pyrido<4,3-b>indole-3-carboxylic acid 
• 17954-23-3 1-ethoxycarbonyl-1,2-dihydroquinoline-2-carbonitrile 
• 52618-53-8 2-(cyanomethyl)-N-ethoxycarbonylindole 
• 143618-95-5 2-[(1-Benzenesulfonyl-1H-indol-2-yl)-ethoxy-methyl]-malonic acid diethyl ester 

Downstream Products

• 74011-07-7 3-acetylamino-1-methyl-5H-pyrido<4,3-b>indole 
• 1028068-11-2 C₁₂H₇Br₃N₂ 
• 623158-31-6 N-pivalyloxy-N-(1-methyl-5H-pyrido[4,3-b]indol-3-yl)acetamide 
• 623158-27-0 N-acetoxy-N-(1-methyl-5H-pyrido[4,3-b]indol-3-yl)acetamide 
• 623158-29-2 N-hydroxy-N-(1-methyl-5H-pyrido[4,3-b]indol-3-yl)acetamide 
• 74317-45-6 3-hydroxyamino-1-methyl-5H-pyrido<4,3-b>indole 
• 75567-58-7 1-methyl-3-nitro-5H-pyrido<4,3-b>indole 

Relevant academic research and scientific papers

Synthesis of Genotoxic Heterocyclic Amines Trp-P-1 and Trp-P-2

Trp-P-1 (1a) and Trp-P-2 (1b) possessing a pyridoindole system have been newly synthesized.The key reaction step in the synthetic sequence has been the thermal electrocyclic reaction of the 1-azahexa-1,3,5-triene system 3 involving the indole bond derived from 2-vinylindoles 4. 2-Vinylindole 4a has been derived from N-(benzenesulfonyl)indole (5) in a four-step sequence. 2-Vinylindole 4b has been synthesized by two routes using either ethoxymethylidene Meldrum's acid (6b) or diethyl ethoxymethylidenemalonate (10) as Michael acceptors to the 2-lithio-N-(benzenesulfonyl)indole.