72299-06-0

Basic information

• Product Name: Pyrrolidine, 1-(cyclohexylacetyl)-
• CAS NO: 72299-06-0
• Molecular Formula: C12H21NO
• Molecular Weight: 195.305
• Mol File: 72299-06-0.mol

Chemical Properties

• CAS DataBase Reference: Pyrrolidine, 1-(cyclohexylacetyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolidine, 1-(cyclohexylacetyl)-(72299-06-0)
• EPA Substance Registry System: Pyrrolidine, 1-(cyclohexylacetyl)-(72299-06-0)

Safety Data

• Hazardous Substances Data: 72299-06-0(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 23860-35-7 cyclohexylacetic acid chloride 

Relevant articles and documents

Chemoselective intermolecular α-arylation of amides

A new approach for the fully chemoselective α-arylation of amides is presented. By means of electrophilic amide activation, aryl groups can be regioselectively introduced α- to amides, even in the presence of esters and alkyl ketones. Mechanistic studies reveal key reaction intermediates and emphasize a remarkably subtle base effect in this transformation. Arylating me softly: A new approach for the fully chemoselective α-arylation of amides has been developed. When electrophilic amide activation is employed, aryl groups can be regioselectively introduced in the position α to the amide, and that even in the presence of esters or alkyl ketones. Mechanistic studies emphasize a remarkably subtle base effect in this transformation.