72302-32-0

Basic information

• Product Name: 1-(phenyl-4-d)ethan-1-one
• Synonyms: 1-(phenyl-4-d)ethan-1-one
• CAS NO: 72302-32-0
• Molecular Weight: 121.143
• Mol File: 72302-32-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-(phenyl-4-d)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(phenyl-4-d)ethan-1-one(72302-32-0)
• EPA Substance Registry System: 1-(phenyl-4-d)ethan-1-one(72302-32-0)

Safety Data

• Hazardous Substances Data: 72302-32-0(Hazardous Substances Data)

Upstream product

• 99-90-1 para-bromoacetophenone 
• 99-91-2 para-chloroacetophenone 
• 13329-40-3 4-Iodoacetophenone 

Downstream Products

• 99-93-4 4-Hydroxyacetophenone 
• 18594-05-3 4-cyclohexylacetophenone 

Relevant articles and documents

A visible-light-photocatalytic water-splitting strategy for sustainable hydrogenation/deuteration of aryl chlorides

Hydrogenation/deuteration of carbon chloride (C?Cl) bonds is of high significance but remains a remarkable challenge in synthetic chemistry, especially using safe and inexpensive hydrogen donors. In this article, a visible-light-photocatalytic watersplitting hydrogenation technology (WSHT) is proposed to in-situ generate active H-species (i.e., Had) for controllable hydrogenation of aryl chlorides instead of using flammable H2. When applying heavy water-splitting systems, we could selectively install deuterium at the C?Cl position of aryl chlorides under mild conditions for the sustainable synthesis of high-valued added deuterated chemicals. Sub-micrometer Pd nanosheets (Pd NSs) decorated crystallined polymeric carbon nitrides (CPCN) is developed as the bifunctional photocatalyst, whereas Pd NSs not only serve as a cocatalyst of CPCN to generate and stabilize H (D)-species but also play a significant role in the sequential activation and hydrogenation/deuteration of C?Cl bonds. This article highlights a photocatalytic-WSHT for controllable hydrogenation/deuteration of low-cost aryl chlorides, providing a promising way for the photosynthesis of high-valued added chemicals instead of the hydrogen evolution.

Dehalogenative Deuteration of Unactivated Alkyl Halides Using D2O as the Deuterium Source

The general dehalogenation of alkyl halides with zinc using D2O or H2O as a deuterium or hydrogen donor has been developed. The method provides an efficient and economic protocol for deuterium-labeled derivatives with a wide substrate scope under mild reaction conditions. Mechanistic studies indicated that a radical process is involved for the formation of organozinc intermediates. The facile hydrolysis of the organozinc intermediates provides the driving force for this transformation.

Intragel photoreduction of aryl halides by green-to-blue upconversion under aerobic conditions

The first proof of concept for the application of intragel green-to-blue photon upconversion to a chemical reaction is reported. The developed method allows the photoreduction of aryl halides at room temperature under aerobic conditions.