723286-87-1

Usage

Uses

Used in Pharmaceutical Industry:
3-(trifluoromethyl)-5,6,7,8-tetrahydro-5-methyl-[1,2,4]triazolo[4,3-a]pyrazine is used as an intermediate in the synthesis of various pharmaceuticals for its ability to form complex structures with other compounds, contributing to the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 3-(trifluoromethyl)-5,6,7,8-tetrahydro-5-methyl-[1,2,4]triazolo[4,3-a]pyrazine serves as a key component in the creation of novel agrochemicals, potentially enhancing crop protection and yield through its integration into pesticides, herbicides, or other agricultural products.
Used in Organic Chemistry Research:
3-(trifluoromethyl)-5,6,7,8-tetrahydro-5-methyl-[1,2,4]triazolo[4,3-a]pyrazine is utilized as a building block in organic chemistry research, where its reactivity and structural features are explored to create new compounds with specific properties for various applications, including materials science and chemical engineering.
Used in Medicinal Chemistry:
3-(trifluoromethyl)-5,6,7,8-tetrahydro-5-methyl-[1,2,4]triazolo[4,3-a]pyrazine is employed in medicinal chemistry as a structural element in drug design, leveraging its unique functional groups to modulate interactions with biological targets, potentially leading to the discovery of new therapeutic agents with enhanced efficacy and selectivity.

InChI:InChI=1/C7H9F3N4/c1-4-2-11-3-5-12-13-6(14(4)5)7(8,9)10/h4,11H,2-3H2,1H3

Upstream product

• 723286-86-0 3-(trifluoromethyl)-5-methyl-[1,2,4]triazolo[4,3-a]pyrazine 
• 19848-57-8 2-hydrazino-6-methylpyrazine 
• 38557-71-0 2-chloro-6-methylpyrazine 

Relevant academic research and scientific papers

QUINOLINE DERIVATIVES AS SMO INHIBITORS

Disclosed are quinoline derivatives as hedgehog pathway inhibitors, especially as SMO inhibitors. Compounds of the present invention can be used in treating diseases relating to hedgehog pathway including cancer.

PIPERAZINOTRIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN DRUG PREPARATION

Provided is a piperazinotriazole compound represented by general formula I or an isomer, a pharmaceutically acceptable salt, ester, prodrug or hydrate thereof. Also provided are a method for preparing the compound, a drug composition containing the compou

Discovery of potent and selective dipeptidyl peptidase IV inhibitors derived from β-aminoamides bearing subsituted triazolopiperazines

A series of β-aminoamides bearing triazolopiperazines have been discovered as potent, selective, and orally active dipeptidyl peptidase IV (DPP-4) inhibitors by extensive structure-activity relationship (SAR) studies around the triazolopiperazine moiety.

3-AMINO-4-PHENYLBUTANOIC ACID DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

The present invention is directed to 3-amino-4-phenylbutanoic acid derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.