7237-08-3Relevant articles and documents
SYNTHESIS OF PRIMARY α-CHLOROPHOSPHINES BY A CHEMOSELECTIVE REDUCTION OF α-CHLOROPHOPHONATES
Cabioch, Jean-Luc,Pellerin, Bruno,Denis, Jean-Marc
, p. 27 - 32 (2007/10/02)
Reduction of chloromethylphosphonates with lithium aluminium hydride gave a mixture of chloromethylphosphine and methylphosphine, characterized by NMR, IR and mass spectra.Reduction of the same compounds by AlH3 gave chloromethylphosphine as nearly the only product.Extension of this reaction to the C-substituted derivatives gave the correspondeng α-chlorophosphines with good chemoselectivity.Keywords: Reduction of phosphonates; aluminium hydride; chemoselectivity; primary phosphines.