72418-40-7

Basic information

• Product Name: 3-Phenylisoxazole-5-carboxaldehyde 97%
• Synonyms: 3-Phenylisoxazole-5-carboxaldehyde 97%;3-PHENYLISOXAZOLE-5-CARBALDEHYDE;3-Phenylisoxazole-5-carboxaldehyde;5-isoxazolecarboxaldehyde, 3-phenyl-;3-phenyl-5-isoxazolecarbaldehyde(SALTDATA: FREE);3-phenyl-1,2-oxazole-5-carbaldehyde;3-phenyl-5-isoxazolecarboxaldehyde;3-Phenylisoxazole-5-carboxaldehyde97%
• CAS NO: 72418-40-7
• Molecular Formula: C₁₀H₇NO₂
• Molecular Weight: 173.17
• Mol File: 72418-40-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: 72.5-74°C
• Boiling Point: 361.5 °C at 760 mmHg
• Flash Point: 172.4 °C
• Appearance: /
• Density: 1.216 g/cm³
• Vapor Pressure: 2.06E-05mmHg at 25°C
• Refractive Index: 1.588
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-Phenylisoxazole-5-carboxaldehyde 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenylisoxazole-5-carboxaldehyde 97%(72418-40-7)
• EPA Substance Registry System: 3-Phenylisoxazole-5-carboxaldehyde 97%(72418-40-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 72418-40-7(Hazardous Substances Data)

Usage

General Description

3-Phenylisoxazole-5-carboxaldehyde 97% is a chemical compound often used in organic and medicinal chemistry. It contains 97% concentration of the active ingredient, indicating its high purity. This chemical, which is a derivative of isoxazole, is generally characterized by its aromatic phenyl group and its aldehyde functional group, resulting in its unique chemical properties. It is commonly employed in chemical research and development, used as a building block or reagent in chemical reactions to synthesize more complex molecules, specifically those with potential applications in medicine and other scientific fields.

InChI:InChI=1/C10H7NO2/c12-7-9-6-10(11-13-9)8-4-2-1-3-5-8/h1-7H

Upstream product

• 5221-17-0 2,3-dibromopropanal 
• 81745-44-0 benzohydroximoyl chloride 
• 135335-38-5 5-dichloromethyl-3-phenyl-isoxazole 
• 624-67-9 Propargylic aldehyde 
• 873-67-6 benzonitrile oxide 
• 932-90-1 Benzaldoxime 
• 100-52-7 benzaldehyde 
• 90924-12-2 3-phenyl-5-hydroxymethylisoxazole 

Downstream Products

• 2048-69-3 5-acetyl-3-phenylisoxazole 
• 337356-30-6 5-Oxo-2-[1-(3-phenyl-isoxazol-5-yl)-meth-(E)-ylidene]-hexanoic acid 
• 337356-17-9 2-[acetoxy-(3-phenyl-isoxazol-5-yl)-methyl]-acrylic acid tert-butyl ester 

Relevant articles and documents

A rapid and efficient solvent-free microwave-assisted synthesis of pyrazolone derivatives containing substituted isoxazole ring

An efficient synthesis of 4-substituted pyrazolone derivatives was developed. 4-Substituted pyrazolone derivatives were synthesized in 78-97% yields starting from various 3-substituted isoxazole-5-carbaldehydes, ethyl acetoacetate and hydrazine under micr

Synthesis of novel 5-(3-alkylquinolin-2-yl)-3-aryl isoxazole derivatives and their cytotoxic activity

The propargyl alcohol on reaction with aldoxime and NaOCl in DCM gave exclusively (3-arylisoxazol-5-yl) methanol 1. The compound 1 was oxidized to an aldehyde 2 followed by reaction with aniline resulted in Schiff's base 3. The compounds 3 were further re

Synthesis and preliminary antibacterial evaluation of 2-butyl succinate-based hydroxamate derivatives containing isoxazole rings

Two series of novel 2-butyl succinate-based Hydroxamate derivatives containing isoxazole rings were synthesized, characterized and evaluated for antibacterial activity. The synthesized compounds were found to exhibit weak to moderate inhibitory activity against Staphytlococcus aureu and Klebsiellar pneumonia in vitro. All the compounds synthesized were found to be more effective against Klebsiellar pneumonia compared to Staphytlococcus aureu.