7244-73-7Relevant academic research and scientific papers
TRPV4 ANTAGONISTS
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Page/Page column 42, (2011/10/13)
The present invention relates to quinoline analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.
Efficient and practical synthesis of dissymmetrical ethers of 4-nitrocatechol
Subashini, Murugan,Balasubramanian, Kalpattu K.,Bhagavathy, Shanmugasundaram
, p. 3088 - 3106 (2008/12/22)
An efficient and practical synthesis of dissymmetrical ethers of 4-nitrocatechol from 5-nitrosalicyladehyde and 2-hydroxy-5-nitroacetophenone via Baeyer-Villiger oxidation is described. These dissymmetrical ethers are useful in the synthesis of various coccidiostats and other important pharmaceutical intermediates. Copyright Taylor & Francis Group, LLC.
THE NUCLEOPHILIC AROMATIC PHOTOSUBSTITUTION IN PHOTOAFFINITY LABELLING. A MODEL STUDY OF A CYCLOHEXIMIDE DERIVATIVE.
Castello, A.,Marquet, J.,Moreno-Manas, M.,Sirera, X.
, p. 2489 - 2492 (2007/10/02)
The photoreactions of several 4-nitrocatechol ethers with the relatively hard nucleophile methylamine occurs at the meta position respect to the nitro group.A derivative of the antibiotic cycloheximide carrying a 4-nitrocatechol ether moiety reacts with methylamine affording an in vitro model for photoaffinity labelling.
