724434-37-1

Basic information

• Product Name: 2-phenyl-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazole
• Synonyms: 2-phenyl-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazole
• CAS NO: 724434-37-1
• Molecular Formula: C15H9F3N2O
• Molecular Weight: 290.2399696
• Mol File: 724434-37-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-phenyl-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazole(724434-37-1)
• EPA Substance Registry System: 2-phenyl-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazole(724434-37-1)

Safety Data

• Hazardous Substances Data: 724434-37-1(Hazardous Substances Data)

Upstream product

• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 613-94-5 benzoic acid hydrazide 
• 65-85-0 benzoic acid 
• 339-59-3 4-(trifluoromethyl)benzoic acid hydrazide 
• 166539-79-3 2,3,4,5,6-pentafluorophenyl 4-(trifluoromethyl)benzoate 
• 455-18-5 4-CF₃C₆H₄CN 
• 100-47-0 benzonitrile 

Relevant articles and documents

Iron(III)/TEMPO-Catalyzed Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles by Oxidative Cyclization under Mild Conditions

A simple and efficient cationic Fe(III)/TEMPO-catalyzed oxidative cyclization of aroyl hydrazones has been developed for the synthesis of 2,5-disubstituted 1,3,4-oxadiazole derivatives. The reaction offers a broad scope, good functional-group tolerance, and high yields under mild conditions in the presence of O 2.

17O NMR studies of substituted 1,3,4-oxadiazoles

Three series of substituted 1,3,4-oxadiazoles were studied by 17O NMR spectroscopy. Chemical shifts values were correlated with empirical Hammett parameters as well as calculated bond lengths and chemical shielding values.