72474-40-9

Basic information

• Product Name: Phenol, 4-(2-chloro-1,2-diphenylethenyl)-, (Z)-
• CAS NO: 72474-40-9
• Molecular Formula: C20H15ClO
• Molecular Weight: 306.791
• Mol File: 72474-40-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Phenol, 4-(2-chloro-1,2-diphenylethenyl)-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-(2-chloro-1,2-diphenylethenyl)-, (Z)-(72474-40-9)
• EPA Substance Registry System: Phenol, 4-(2-chloro-1,2-diphenylethenyl)-, (Z)-(72474-40-9)

Safety Data

• Hazardous Substances Data: 72474-40-9(Hazardous Substances Data)

Upstream product

• 140868-82-2 (E)-(2-bromo-1-chloro-2-iodovinyl)benzene 
• 5720-07-0 4-methoxyphenylboronic acid 
• 98-80-6 phenylboronic acid 
• 536-74-3 phenylacetylene 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 501-65-5 diphenyl acetylene 
• 72474-42-1 (Z)-(1-chloro-2-(4-methoxyphenyl)ethene-1,2-diyl)dibenzene 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 53775-08-9 4-(2-chloro-1,2-diphenylvinyl)anisole 

Downstream Products

• 911-45-5 Zuclomiphene 
• 911-45-5 clomiphene 
• 74971-98-5 (Z)-3-<4-(2-chloro-1,2-diphenylvinyl)phenoxy>propanoic acid 
• 74971-96-3 (Z)-3-<4-(2-chloro-1,2-diphenylvinyl)phenoxy>propan-1-ol 
• 74971-94-1 (Z)-3-<4-(2-chloro-1,2-diphenylvinyl)phenoxy>prop-1-ene 

Relevant articles and documents

TEMPO-Regulated Regio- and Stereoselective Cross-Dihalogenation with Dual Electrophilic X+ Reagents

A TEMPO catalyzed cross-dihalogenation reaction was established via redox-regulation of the otherwise complex system of dual electrophilic X+ reagents. Formally, the ICl, BrCl, I2 and Br2 were generated in-situ, which enabled high regio- or stereoselective access to a myriad of iodochlorination, bromochlorination and homo-dihalogenation products with a wide spectrum of functionalities. With its mild conditions and operational simplicity, this method could enable wide applications in organic synthesis, which was exemplified by divergent synthesis of two pharmaceuticals. Detailed mechanistic investigations via radical clock reaction, pinacol ring expansion and Hammett experiments were conducted, which confirmed the intermediacy of halonium ion. In addition, a dynamic catalytic model based on the versatile catalytic role of TEMPO was proposed to explain the selective outcomes.

Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis

The present invention relates to a method of using triaryl-ethylene derivatives in the treatment or prevention bone tissue loss or osteoporosis.

Triarylhaloethylenes as gonadotrophin inhibitors

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