724772-41-2Relevant academic research and scientific papers
Highly efficient double-activation catalysts for the synthesis of ketone cyanohydrins
Chen, Fu-Xue,Liu, Xiaohua,Qin, Bo,Zhou, Hui,Feng, Xiaoming,Zhang, Guolin
, p. 2266 - 2272 (2004)
Tertiary cyanohydrin trimethylsilyl ethers were synthesized in excellent chemical yields by using salen-Al complex (0.25 mol%) and N-oxide (0.5 mol%) without solvent at ambient temperature. The relationship between the ligand structure and catalyst effici
Synthesis, characterization, and reactivity of lanthanide amides incorporating neutral pyrrole ligand. Isolation and characterization of active catalyst for cyanosilylation of ketones
Wang, Fenhua,Wei, Yun,Wang, Shaowu,Zhu, Xiancui,Zhou, Shuangliu,Yang, Gaosheng,Gu, Xiaoxia,Zhang, Guangchao,Mu, Xiaolong
, p. 86 - 93 (2015/01/30)
A series of lanthanide amido complexes incorporating a neutral pyrrole ligand were synthesized and characterized, and their catalytic activities were studied. Treatment of [(Me3Si)2N]3Ln(μ-Cl)Li(THF)3 with 1 equ
Phenolic N-oxide as a highly efficient organocatalyst for cyanosilylation of ketones
Li, Yan,He, Bin,Feng, Xiaoming,Zhang, Guolin
, p. 1598 - 1600 (2007/10/03)
The use of an inexpensive, easy to handle and readily available chemical, 5 mol% phenolic N-oxide, alone as a catalyst for cyanosilylation of ketones gave the corresponding products in 78-99% yield with reaction times of 0.5-16 hours.
Asymmetric Cyanosilylation of Ketones Catalyzed by Bifunctional Chiral N-Oxide Titanium Complex Catalysts
Shen, Yongcun,Feng, Xiaoming,Li, Yan,Zhang, Guolin,Jiang, Yaozhong
, p. 129 - 137 (2007/10/03)
A new bifunctional catalytic system based on chiral N-oxide titanium complexes has been used for the asymmetric cyanosilylation of ketones. Screening of a variety of chiral N-oxide metal complexes resulted in (1R,2S)-1-(2'-pyridylmethyl)-2-(diphenylhydroxymethyl)pyrrolidine N-oxide titanium complex, which gave O-TMS cyanohydrins in good yields with enantiometric excesses of up to 69 percent. A catalytic cycle based on experimental phenomena and studies was proposed to explain the origin of the asymmetric induction.
Influence of an α-Cyano Function on Charge Delocalization in the Benzyl Cation. Relationship between Inductive Destabilization and Conjugative Stabilization by the Cyano Group
Gassman, Paul G.,Guggenheim, Thomas L.
, p. 3023 - 3026 (2007/10/02)
The solvolytic behavior of a series of substituted acetophenone cyanohydrin methanesulfonates has been studied in 2,2,2-trifluoroethanol.A ρ value of -6.70 was observed when the rate data was evaluated vs.Brown's ?+ values.
