725250-70-4

Basic information

• Product Name: (Z)-3-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-phenyl-ethylamino]-but-2-enoic acid methyl ester
• Synonyms: (Z)-3-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-phenyl-ethylamino]-but-2-enoic acid methyl ester
• CAS NO: 725250-70-4
• Molecular Weight: 349.546
• Mol File: 725250-70-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-3-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-phenyl-ethylamino]-but-2-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-phenyl-ethylamino]-but-2-enoic acid methyl ester(725250-70-4)
• EPA Substance Registry System: (Z)-3-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-phenyl-ethylamino]-but-2-enoic acid methyl ester(725250-70-4)

Safety Data

• Hazardous Substances Data: 725250-70-4(Hazardous Substances Data)

Upstream product

• 120417-13-2 (S)-2-(tert-butyldimethylsilyloxy)-1-phenylethylamine 
• 105-45-3 acetoacetic acid methyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 20989-17-7 (2S)-2-phenylglycinol 

Downstream Products

• 476187-19-6 (1S)-(2S)-(3S)-1-(2-hydroxy-1-phenyl-ethyl)-2-methyl-piperidine-3-carboxylic acid methyl ester 
• 595582-07-3 1-(2-hydroxy-(1S)-phenyl-ethyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid methyl ester 
• 454451-70-8 (3S)-(8R)-(8aR)-methyl-5-oxo-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-8-carboxylic acid methyl ester 
• 595582-03-9 1-[2-(tert-butyl-dimethyl-silanyloxy)-(1S)-phenyl-ethyl]-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid methyl ester 

Relevant articles and documents

Enantioselective synthesis of indolizidine and quinolizidine derivatives from chiral non-racemic bicyclic lactams

Chiral non-racemic bicyclic lactams 2b,c, derived from (R)- and (S)-phenylglycinol, were used in the enantioselective synthesis of (-)-lupinine and 5-epitashiromine, respectively. The efficiency of the synthesis relied on the high diastereoselectivities of formation and reduction of compounds 2b,c.