72536-35-7

Upstream product

• 63281-70-9 2,6-bis-(4-acetoxy-3-methoxyphenyl)-3,7-dioxabicyclo<3.3.0>octane-4,8-dione 
• 72536-37-9 4,8-dimethoxypinoresinol 
• 38209-42-6 threo-2,3-bis-(α-hydroxy-4-hydroxy-3-methoxybenzyl)butane-1,4-diol 
• 77550-11-9 4-cis,8-cis-bis(4-hydroxy-3-methoxyphenyl)-3,7-dioxabicyclo<3.3.0>octane-2,6-dione 
• 1135-24-6 (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid 
• 108-24-7 acetic anhydride 
• 72536-33-5 4,8-dihydroxypinoresinol 
• 458-35-5 coniferol 
• 1135-24-6 3-(4-hydroxy-3-methoxyphenyl)acrylic acid 
• 72536-33-5 2,6-exo-bis(4-hydroxy-3-methoxyphenyl)-4,8-exo-dihydroxy-3,7-dioxabicyclo<3.3.0>octane 

Relevant academic research and scientific papers

Synthesis and 1H N.M.R. Spectroscopic Analysis of Some 3,7-Dioxabicyclooctane Lignans

Within the framework of a synthetic project towards the preparation of the natural germination inhibitor 2,6-diaryl-3,7-dioxabicyclooctane, several molecules with the same bicyclic skeleton were prepared and their 1H n.m.r. spectra are described in detail.For the symmetrical systems particularly, the spectra exhibited second-order features and were interpreted analytically or, when necessary, by computer simulation.These n.m.r. data enabled a conformational analysis of the ring system.

Synthesis of 2,6-Diaryl-4,8-dihydroxy-3,7-dioxabicyclooctanes

A series of 2,6-diaryl-4,8-dihydroxy-3,7-dioxabicyclooctanes, including 4,8-dihydroxysesamin, a naturally occurring lignan, have been prepared via the corresponding dilactones.The 1H and 13C n.m.r. spectra have been compared and the bistoluene-p-sulphonate of 4,8-dihydroxyeudesmin has been reduced by lithium aluminium hydride to give (+/-)-eudesmin.Since this synthesis does not involve ring-opened intermediates and starts from a dilactone of established structure, it represents the first unequivocal synthesis of such a lignan.