72539-10-7

Basic information

• Product Name: Acetamide, 2-[(4-methylphenyl)sulfonyl]-N-phenyl-
• CAS NO: 72539-10-7
• Molecular Formula: C15H15NO3S
• Molecular Weight: 289.355
• Mol File: 72539-10-7.mol

Chemical Properties

• CAS DataBase Reference: Acetamide, 2-[(4-methylphenyl)sulfonyl]-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2-[(4-methylphenyl)sulfonyl]-N-phenyl-(72539-10-7)
• EPA Substance Registry System: Acetamide, 2-[(4-methylphenyl)sulfonyl]-N-phenyl-(72539-10-7)

Safety Data

• Hazardous Substances Data: 72539-10-7(Hazardous Substances Data)

Upstream product

• 102-01-2 N-phenylacetoacetamide 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 657-84-1 sodium tosylate 
• 587-65-5 N-chloroacetyl-aniline 
• 5326-87-4 N-(phenyl)bromoacetamide 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 62-53-3 aniline 
• 3185-99-7 Methyl p-tolyl sulfone 

Relevant articles and documents

O -Iodoxybenzoic Acid (IBX)-Iodine Mediated One-Pot Deacylative Sulfonylation of 1,3-Dicarbonyl Compounds: A Synthesis of β-Carbonyl Sulfones

A combination of o-iodoxybenzoic acid (IBX) and a catalytic amount of iodine is found to promote a facile one-pot deacylative sulfonylation reaction of 1,3-dicarbonyl compounds with sodium sulfinates to yield β-carbonyl sulfones. The present method provides the target products bearing a wide variety of functional groups in one step and in good yields.

An efficient electrochemical synthesis of β-keto sulfones from sulfinates and 1,3-dicarbonyl compounds

An efficient electrochemical synthesis of β-keto sulfones from sulfinates and 1,3-dicarbonyl compounds has been developed. The present electrochemical route could afford the target products in high to excellent yields under mild conditions.

Reaction of different α-sulfonyl acetamides with methyl acrylate

The base-induced tandem-coupling/cyclization reactions of various α-sulfonyl acetamide derivatives A with methyl acrylate differentiated between two different pathways to form α-sulfonyl analogs of glutarimides B and 2-hydroxycyclohexenecarboxylic acid derivatives C in different ratios. The reaction of α-sulfonyl acetamide dianion with methyl acrylate depended on three factors: the stability of the dianion, concentration of methyl acrylate and the structure of sufonyl and amide substituents. By changing the reaction conditions, we efficiently controlled the cycloaddition reaction to synthesize the desired product, each of which has potential biological activities. A ring closure mechanism is proposed for the reactions.

A Novel Synthesis of Sulfones via the O,O-Diethylphosphorotellurite Ion-Assisted Coupling of Arenesulfonyl Chlorides with Active Halides

Arenesulfonyl chlorides undergo a facile onepot coupling reaction with active halides assisted by sodium O,O-diethylphosphorotellurite to give the corresponding sulfones in excellent yield.