7255-89-2 Usage
Description
1-Benzyl-N-(2-nitrophenyl)piperidin-4-amine is a synthetic chemical compound characterized by its molecular structure that includes a benzyl group, a nitrophenyl group, and a piperidin-4-amine group. It is a compound of interest in the realm of medicinal chemistry and pharmaceutical research, known for its potential as a pharmacological agent for the development of novel therapeutic drugs.
Uses
Used in Pharmaceutical Research:
1-Benzyl-N-(2-nitrophenyl)piperidin-4-amine is used as a research compound for exploring its biological activity and potential medicinal uses. Its unique molecular structure positions it as a candidate for further studies in drug development, particularly for the treatment of various medical conditions.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-Benzyl-N-(2-nitrophenyl)piperidin-4-amine is utilized as a key intermediate in the synthesis of new drugs. Its structural components allow for the design and modification of pharmaceutical agents that could address specific therapeutic needs.
Used in Drug Development:
1-Benzyl-N-(2-nitrophenyl)piperidin-4-amine is employed as a precursor in the development of drugs targeting specific medical conditions. Its potential as a pharmacological agent is being investigated for its efficacy and safety in treating diseases, making it a valuable asset in the creation of novel therapeutic solutions.
Check Digit Verification of cas no
The CAS Registry Mumber 7255-89-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,5 and 5 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7255-89:
(6*7)+(5*2)+(4*5)+(3*5)+(2*8)+(1*9)=112
112 % 10 = 2
So 7255-89-2 is a valid CAS Registry Number.
InChI:InChI=1/C18H21N3O2/c22-21(23)18-9-5-4-8-17(18)19-16-10-12-20(13-11-16)14-15-6-2-1-3-7-15/h1-9,16,19H,10-14H2
7255-89-2Relevant articles and documents
From hit to lead. Combining two complementary methods for focused library design. Application to μ opiate ligands
Poulain,Horvath,Bonnet,Eckhoff,Chapelain,Bodinier,Déprez
, p. 3378 - 3390 (2007/10/03)
Compound 1 obtained by random screening and displaying a micromolar activity on the μ opiate receptor was chosen as a starting point for optimization. Two complementary concepts of similarity were used for the design of analogues and compared. These are based, respectively, on a computer-aided comparison of pharmacophoric patterns and on topological similarity. The structure-activity relationships are discussed in light of both similarity concepts. Compound 40, an N-methyl-3-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decyl)acetamide derivative, designed by combining the structure-activity relationships enlightened by each method, has a subnanomolar affinity for μ (h) receptor (IC50=0.9 nM). It is a promising lead, allowing the design of a new series of analogues substituted at the N-3 of the spirocycle moiety.
Dipeptides which promote release of growth hormone
-
, (2008/06/13)
Compounds of formula (I) are growth hormone releasing peptide mimetics which are useful for the treatment and prevention of osteoporosis. STR1
