7255-89-2 Usage
General Description
1-Benzyl-N-(2-nitrophenyl)piperidin-4-amine is a chemical compound with a molecular structure consisting of a benzyl group, a nitrophenyl group, and a piperidin-4-amine group. It is a synthetic compound that is commonly used in the field of medicinal chemistry and pharmaceutical research. This chemical is of interest due to its potential as a pharmacological agent, particularly in the development of novel drugs for various therapeutic applications. Its molecular properties and structure make it a candidate for further studies on its biological activity and potential medicinal uses. Additionally, it may also have implications in drug development for the treatment of certain medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 7255-89-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,5 and 5 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7255-89:
(6*7)+(5*2)+(4*5)+(3*5)+(2*8)+(1*9)=112
112 % 10 = 2
So 7255-89-2 is a valid CAS Registry Number.
InChI:InChI=1/C18H21N3O2/c22-21(23)18-9-5-4-8-17(18)19-16-10-12-20(13-11-16)14-15-6-2-1-3-7-15/h1-9,16,19H,10-14H2
7255-89-2Relevant articles and documents
From hit to lead. Combining two complementary methods for focused library design. Application to μ opiate ligands
Poulain,Horvath,Bonnet,Eckhoff,Chapelain,Bodinier,Déprez
, p. 3378 - 3390 (2007/10/03)
Compound 1 obtained by random screening and displaying a micromolar activity on the μ opiate receptor was chosen as a starting point for optimization. Two complementary concepts of similarity were used for the design of analogues and compared. These are based, respectively, on a computer-aided comparison of pharmacophoric patterns and on topological similarity. The structure-activity relationships are discussed in light of both similarity concepts. Compound 40, an N-methyl-3-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decyl)acetamide derivative, designed by combining the structure-activity relationships enlightened by each method, has a subnanomolar affinity for μ (h) receptor (IC50=0.9 nM). It is a promising lead, allowing the design of a new series of analogues substituted at the N-3 of the spirocycle moiety.
Dipeptides which promote release of growth hormone
-
, (2008/06/13)
Compounds of formula (I) are growth hormone releasing peptide mimetics which are useful for the treatment and prevention of osteoporosis. STR1
