72568-90-2Relevant academic research and scientific papers
Highly Efficient Enantioselective Synthesis of Chiral Sulfones by Rh-Catalyzed Asymmetric Hydrogenation
Yan, Qiaozhi,Xiao, Guiying,Wang, Ying,Zi, Guofu,Zhang, Zhanbin,Hou, Guohua
supporting information, p. 1749 - 1756 (2019/01/25)
A highly efficient and enantioselective Rh-(R,R)-f-spiroPhos complex catalyzed hydrogenation of a series of unsaturated sulfones has been developed. With Rh-(R,R)-f-spiroPhos catalyst under mild conditions, not only the asymmetric hydrogenation of both the 3,3-diaryl and exocyclic α,β-unsaturated sulfones was first realized with up to 99.9% ee but also 3-alkyl-3-aryl and benzo[b]thiophene-1,1-dioxides were successfully hydrogenated to the corresponding chiral sulfones with excellent enantioselectivities (up to 99.4% ee) regardless of the steric hindrance, electronic property, and geometry of the substrates. Moreover, this reaction offers a route to (S)-(+)-ar-turmerone as a spice flavor, which is an important synthetic intermediate of pharmaceuticals.
Samarium(II) iodide-mediated deoxygenative debromination of α-bromo-β-hydroxy (acetoxy) phenyl sulfones: Synthesis of α,β-unsaturated sulfones
Reutrakul, Vichai,Jarussophon, Suwatchai,Pohmakotr, Manat,Chaiyasut, Yupa,U-Thet, Saengvimon,Tuchinda, Patoomratana
, p. 2285 - 2288 (2007/10/03)
Deoxygenative debromination of α-bromo-β-hydroxy (acetoxy) phenyl sulfones with samarium(II) iodide led to substituted α,β-unsaturated sulfones in good to excellent yields. The E-isomer is the major product. A possible mechanism via an α-sulfonyl radical pathway is proposed.
Directed Diastereotopic Lithiation of β-Heterosubstituted Alkyl Sulfones
Eisch, John J.,Galle, James E.
, p. 4534 - 4536 (2007/10/02)
The directed, highly diastereoselective lithiation of β-aminoalkyl sulfones by organolithium reagents has been shown capable of producing either diastereomeric lithio derivative with greater than 90percent selectivity, depending upon the type of amino group.
THE SOLUTION PHOTOCHEMISTRY OF αβ-UNSATURATED SULPHONES
El Tabei, M. A. A. M.,Kirby, Neil V.,Reid, Stewart T.
, p. 565 - 566 (2007/10/02)
1-Phenyl-2-(benzenesulphonyl)-ethylene and 1-phenyl-2-(benzenesulphonyl)-prop-1-ene have been shown to undergo Z,E-photoisomerisation, whereas 2-benzenesulphonylindene readily forms ?2 + ?2> photoadducts with 2,3-dimethylbut-2-ene, cyclopentene, and cyclohexene.
