72578-86-0

Basic information

• Product Name: 1-Methyl-(3-trimethylsilyl)pyrrolidone-2
• Synonyms: 1-Methyl-(3-trimethylsilyl)pyrrolidone-2;1-Methyl-3-(triMethylsilyl)-2-Pyrrolidinone
• CAS NO: 72578-86-0
• Molecular Formula: C₈H₁₇NOSi
• Molecular Weight: 0
• Mol File: 72578-86-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 234.9°C at 760 mmHg
• Flash Point: 95.9°C
• Appearance: /
• Density: 0.93g/cm³
• Vapor Pressure: 0.0516mmHg at 25°C
• Refractive Index: 1.458
• CAS DataBase Reference: 1-Methyl-(3-trimethylsilyl)pyrrolidone-2(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-(3-trimethylsilyl)pyrrolidone-2(72578-86-0)
• EPA Substance Registry System: 1-Methyl-(3-trimethylsilyl)pyrrolidone-2(72578-86-0)

Safety Data

• Hazardous Substances Data: 72578-86-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H17NOSi/c1-9-6-5-7(8(9)10)11(2,3)4/h7H,5-6H2,1-4H3

Upstream product

• 74-83-9 methyl bromide 
• 138142-34-4 3-Trimethylsilyl-2-pyrrolidone 
• 872-50-4 1-methyl-pyrrolidin-2-one 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 587874-15-5 1,3-dimethyl-3-(5'-methoxy-2'-nitrophenyl)pyrrolidin-2-one 
• 587874-16-6 1-N-methyl-3-(5'-methoxy-2'-nitrophenyl)pyrrolidin-2-one 
• 102680-33-1 1,3-dimethyl-3-(2'-amino-5'-methoxyphenyl)pyrrolidin-2-one 
• 107470-28-0 1-methyl-3-trifluoroacetyl-2-pyrrolidinone 

Relevant articles and documents

Synthesis of quaternary α-perfluoroalkyl lactams via electrophilic perfluoroalkylation

Efficient protocols enabling the rapid installation of trifluoromethyl, as well as further functionalized fluoroalkyl groups by an electrophilic perfluoroalkylation of lactam-derived ketene silyl amides (KSAs) using hypervalent iodine reagents 1 and 2 have been developed.

SYNTHESIS AND PROPERTIES OF α-SILYLATED 2-PYRROLIDONE DERIVATIVES

A method has been described for the synthesis of previously unreported α-silylated N-substituted 2-pyrrolidone derivatives and a study was carried out on the reactions of these compounds with lithium aluminium hydride and electrophilic reagents.