72590-77-3 Usage
Description
Hydrocortisone butyrate propionate is a potent, topical steroid reported to possess
minimal systemic side effects. It is indicated in the treatment of various acute
and chronic contact, eczematous, and atopic dermatoses and psoriasis.
Originator
Taiaho (Japan)
Uses
A synthetic adrenocorticosteroid that acts as an anti-inflammatory and anti-pruritic agents. It is used as a topical for the treatment of dermatologic disorders such as atopic dermatitis and psoriasis.
Brand name
Glucocorticoid Pandel
(Savage).
Check Digit Verification of cas no
The CAS Registry Mumber 72590-77-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,5,9 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 72590-77:
(7*7)+(6*2)+(5*5)+(4*9)+(3*0)+(2*7)+(1*7)=143
143 % 10 = 3
So 72590-77-3 is a valid CAS Registry Number.
InChI:InChI=1/C28H40O7/c1-5-7-24(33)35-28(22(31)16-34-23(32)6-2)13-11-20-19-9-8-17-14-18(29)10-12-26(17,3)25(19)21(30)15-27(20,28)4/h14,19-21,25,30H,5-13,15-16H2,1-4H3/t19-,20-,21-,25+,26-,27-,28-/m0/s1
72590-77-3Relevant articles and documents
Novel hydrocortisone derivative
-
, (2008/06/13)
17α-butyryloxy-11β-hydroxy-21-propionyloxy-4-pregnen-3,20-dione, i.e., hydrocortisone 17-butyrate 21-propionate of the present invention is prepared by acylating hydrocortisone 17-butyrate with propionic acid anhydride or halide. The compound of the present invention has excellent anti-inflammatory effect, percutaneous absorption and less side effect.
