72590-77-3 Usage
Uses
Used in Dermatology:
11beta,17,21-trihydroxypregn-4-ene-3,20-dione 17-butyrate 21-propionate is used as a topical agent for the treatment of dermatologic disorders such as atopic dermatitis and psoriasis. It is effective in managing acute and chronic contact, eczematous, and atopic dermatoses, as well as psoriasis, due to its potent anti-inflammatory and anti-pruritic properties.
Originator
Taiaho (Japan)
Check Digit Verification of cas no
The CAS Registry Mumber 72590-77-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,5,9 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 72590-77:
(7*7)+(6*2)+(5*5)+(4*9)+(3*0)+(2*7)+(1*7)=143
143 % 10 = 3
So 72590-77-3 is a valid CAS Registry Number.
InChI:InChI=1/C28H40O7/c1-5-7-24(33)35-28(22(31)16-34-23(32)6-2)13-11-20-19-9-8-17-14-18(29)10-12-26(17,3)25(19)21(30)15-27(20,28)4/h14,19-21,25,30H,5-13,15-16H2,1-4H3/t19-,20-,21-,25+,26-,27-,28-/m0/s1
72590-77-3Relevant academic research and scientific papers
Novel hydrocortisone derivative
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, (2008/06/13)
17α-butyryloxy-11β-hydroxy-21-propionyloxy-4-pregnen-3,20-dione, i.e., hydrocortisone 17-butyrate 21-propionate of the present invention is prepared by acylating hydrocortisone 17-butyrate with propionic acid anhydride or halide. The compound of the present invention has excellent anti-inflammatory effect, percutaneous absorption and less side effect.
