72607-35-3

Basic information

• Product Name: Benzaldehyde, 3-(1,1-dimethylethyl)-2-hydroxy-5-nitro-
• Synonyms: 3-tert-butyl-2-hydroxy-5-nitrobenzaldeyhe;3-t-butyl-5-nitro-2-hydroxybenzaldehyde;3-(tert-butyl)-5-nitrosalicylaldehyde;Benzaldehyde,3-(1,1-dimethylethyl)-2-hydroxy-5-nitro;3-tert-butyl-2-hydroxy-5-nitro-benzaldehyde;2-hydroxy-3-(tert-butyl)-5-nitrobenzaldehyde;2-hydroxy-3-(1,1-dimethylethyl)-5-nitrobenzaldehyde
• CAS NO: 72607-35-3
• Molecular Formula: C11H13NO4
• Molecular Weight: 223.229
• Mol File: 72607-35-3.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 3-(1,1-dimethylethyl)-2-hydroxy-5-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 3-(1,1-dimethylethyl)-2-hydroxy-5-nitro-(72607-35-3)
• EPA Substance Registry System: Benzaldehyde, 3-(1,1-dimethylethyl)-2-hydroxy-5-nitro-(72607-35-3)

Safety Data

• Hazardous Substances Data: 72607-35-3(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 24623-65-2 3-tert-butyl-2-hydroxybenzaldehyde 
• 64-19-7 acetic acid 
• 88-18-6 2-tert-Butylphenol 

Downstream Products

• 372137-84-3 3-tert-butyl-2-hydroxy-5-nitrobenzoic acid 
• 1262033-70-4 2-tBu-4-NO₂-6-(CH=NiPr)C₆H₂OH 
• 1470070-14-4 C₂₈H₃₆N₄O₆ 
• 1470070-14-4 6,6'-((1E,1'E)-(cyclohexane-1,2-diylbis(azanylylidene))bis(methanylylidene))bis(2-(tert-butyl)-4-nitrophenol) 
• 1383053-07-3 2-(diacetoxymethyl)-6-tert-butyl-4-nitrophenyl acetate 

Relevant articles and documents

Stereoselective protonation of 2-methyl-1-tetralone lithium enolate catalyzed by salan-type diamines

Asymmetric protonation of ketone enolates is a convenient alternative to asymmetric alkylation of enolates that allows to convert racemic ketones into their optically active form. Here, we have reported an efficient enantioselective protonation of 2-methyl-1-tetralone lithium enolate catalyzed by salan-type diamines. A broad series of salan-type catalysts were synthesized, including several previously unknown, and subsequently tested in the title reaction. For the first time, a chiral amine used as organocatalyst has shown better results than as stoichiometric protonating agent. Application of only 10 mol% of salan allows to obtain the title ketone with high yield and enantiomeric excess up to 75%. The DFT calculations of the structure of the catalyst and its complex with lithium enolate were conducted, which makes it possible to propose a likely reaction mechanism.

Mononuclear Salen-Sodium Ion Pairs as Catalysts for Isoselective Polymerization of rac-Lactide

A series of mononuclear salen-sodium anions, as the first examples, were synthesized with tetra-alkyl ammonium as a counterpart cation. These complexes are efficient catalysts for the isoselective ring-opening polymerization of rac-lactide; the molecular weights of polymers are under control and molecular weight distributions are narrow when five equivalents of BnOH is used as an initiator. The best isoselectivity value of Pm = 0.82 was achieved at -70 °C. The experimental results together with a density functional theory calculation show that a ligand-assisted activated monomer mechanism is more reasonable than an activated monomer mechanism for this system.

Preparation, Characterization and Reactivity of a Bis-hypochlorite Adduct of a Chiral Manganese(IV) Salen Complex

A bis-hypochlorite adduct of a manganese(IV) salen complex having a chiral (R,R)-cyclohexane-1,2-diamine linkage (2-tBu) is successfully prepared and characterized by various spectroscopic methods. The reactions of 2-tBu with various organic substrates show that 2-tBu is capable of sulfoxidation, epoxidation, chlorination, and hydrogen abstraction reactions. However, the enantioselectivity of the epoxidation reactions by 2-tBu is much lower than that reported for the catalytic reactions by Jacobsen's catalyst. The low enantioselectivity is consistent with a planar conformation of the salen ligand, which is suggested by circular dichroism spectroscopy. This study suggests that 2-tBu is not a reactive intermediate of Jacobsen's enantioselective epoxidation catalysis.