72655-88-0

Basic information

• Product Name: 2-Hydroxy-3-phenyl-3-butensaeureaethylester
• CAS NO: 72655-88-0
• Molecular Weight: 206.241
• Mol File: 72655-88-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Hydroxy-3-phenyl-3-butensaeureaethylester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxy-3-phenyl-3-butensaeureaethylester(72655-88-0)
• EPA Substance Registry System: 2-Hydroxy-3-phenyl-3-butensaeureaethylester(72655-88-0)

Safety Data

• Hazardous Substances Data: 72655-88-0(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 77-83-8 fraeseol 

Downstream Products

• 58671-14-0 ethyl-2-acetoxy-3-phenyl-3-butenoate 
• 894421-56-8 (Z)-ethyl 4-azido-3-phenylbut-2-enoate 
• 1374981-53-9 ethyl 2-(methylsulfonyloxy)-3-phenylbut-3-enoate 

Relevant articles and documents

HClO4·SiO2-mediated improved isomerization of glycidic esters to α-hydroxy-β,γ -unsaturated esters: Application in the formal synthesis of (R)-Baclofen and β-phenyl GABA analogues

An efficient isomerization of glycidic esters to corresponding allylic alcohols, viz. α-hydroxy-β,γ -unsaturated esters has been brought about using HClO4·SiO2. Five of these allylic alcohols underwent selective SN2' nucleophilic substitution to generate γ-azido-α,β-unsaturated esters which were readily converted to an antispastic drug Baclofen and four other β-phenyl GABA analogues.