894421-56-8

Basic information

• Product Name: (Z)-ethyl 4-azido-3-phenylbut-2-enoate
• Synonyms: (Z)-ethyl 4-azido-3-phenylbut-2-enoate
• CAS NO: 894421-56-8
• Molecular Weight: 231.254
• Mol File: 894421-56-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-ethyl 4-azido-3-phenylbut-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-ethyl 4-azido-3-phenylbut-2-enoate(894421-56-8)
• EPA Substance Registry System: (Z)-ethyl 4-azido-3-phenylbut-2-enoate(894421-56-8)

Safety Data

• Hazardous Substances Data: 894421-56-8(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 72655-88-0 2-Hydroxy-3-phenyl-3-butensaeureaethylester 
• 1374981-53-9 ethyl 2-(methylsulfonyloxy)-3-phenylbut-3-enoate 
• 77-83-8 fraeseol 
• 623-70-1 ethyl (E)-crotonate 
• 945-93-7 ethyl (E)-3-phenylbut-2-enoate 
• 98-80-6 phenylboronic acid 
• 143704-79-4 (Z)-ethyl 4-bromo-3-phenylbut-2-enoate 

Downstream Products

• 71657-88-0 (4R)-4-phenyl-2-pyrrolidone 
• 62624-45-7 (S)-4-phenyl-1-tosylpyrrolidin-2-one 

Relevant articles and documents

HClO4·SiO2-mediated improved isomerization of glycidic esters to α-hydroxy-β,γ -unsaturated esters: Application in the formal synthesis of (R)-Baclofen and β-phenyl GABA analogues

An efficient isomerization of glycidic esters to corresponding allylic alcohols, viz. α-hydroxy-β,γ -unsaturated esters has been brought about using HClO4·SiO2. Five of these allylic alcohols underwent selective SN2' nucleophilic substitution to generate γ-azido-α,β-unsaturated esters which were readily converted to an antispastic drug Baclofen and four other β-phenyl GABA analogues.