72676-69-8 Usage
Explanation
Different sources of media describe the Explanation of 72676-69-8 differently. You can refer to the following data:
1. This is the chemical name of the compound, which is derived from its structural formula.
2. Lomustine is the name used for this chemical compound in pharmaceutical products and medical contexts.
3. Nitrosoureas are a class of chemotherapeutic agents that contain a nitroso group (-NO) and a urea group (-NH2) in their molecular structure.
4. Lomustine is used as a chemotherapy drug to treat various types of cancer, such as brain tumors and Hodgkin's lymphoma.
5. Lomustine disrupts the processes of DNA replication and transcription in cancer cells, leading to their death and preventing the growth and spread of cancer.
6. Lomustine is taken by mouth in the form of capsules and is absorbed into the bloodstream to reach the cancer cells.
7. Lomustine has been found to be effective in controlling the growth and spread of some cancer types, improving the prognosis for patients.
8. Lomustine can cause a range of side effects due to its potent nature, affecting the bone marrow, liver, and lungs, among other organs.
9. Due to the potential side effects and the need for careful monitoring, lomustine is only available through a prescription from a healthcare professional.
10. The administration, dosage, and monitoring of side effects of lomustine require the expertise of a healthcare professional to ensure its safe and effective use.
Chemical Class
Nitrosoureas
Use
Chemotherapy medication
Mechanism of Action
Interferes with DNA synthesis and RNA production in cancer cells
Administration
Oral
Effectiveness
Slowing down the progression of certain types of cancer
Side Effects
Bone marrow suppression, liver toxicity, lung fibrosis, etc.
Prescription
Available by prescription only
Supervision
Should be used under the guidance of a healthcare professional
Check Digit Verification of cas no
The CAS Registry Mumber 72676-69-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,6,7 and 6 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 72676-69:
(7*7)+(6*2)+(5*6)+(4*7)+(3*6)+(2*6)+(1*9)=158
158 % 10 = 8
So 72676-69-8 is a valid CAS Registry Number.
72676-69-8Relevant articles and documents
Synthesis and Anticancer Activity of Nitrosourea Derivatives of Phensuximide
Crider, A. Michael,Kolczynski, Thomas M.,Yates, Kathleen M.
, p. 324 - 326 (2007/10/02)
Nitrosourea derivatives 9-13 which utilize phensuximide (1) as the carrier were synthesized as potential central nervous system antitumor agents.The N-(2-chloroethyl)-N-nitrosourea 13 was active in the mouse ependymoblastoma brain-tumor system, as well as
