72680-08-1

Basic information

• Product Name: ethyl 5-amino-1-p-tolyl-1H-1,2,3-triazole-4-carboxylate
• Synonyms: ethyl 5-amino-1-p-tolyl-1H-1,2,3-triazole-4-carboxylate
• CAS NO: 72680-08-1
• Molecular Weight: 246.269
• Mol File: 72680-08-1.mol

Chemical Properties

• CAS DataBase Reference: ethyl 5-amino-1-p-tolyl-1H-1,2,3-triazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-amino-1-p-tolyl-1H-1,2,3-triazole-4-carboxylate(72680-08-1)
• EPA Substance Registry System: ethyl 5-amino-1-p-tolyl-1H-1,2,3-triazole-4-carboxylate(72680-08-1)

Safety Data

• Hazardous Substances Data: 72680-08-1(Hazardous Substances Data)

Upstream product

• 2101-86-2 p-methylazidobenzene 
• 105-56-6 ethyl 2-cyanoacetate 
• 106-49-0 p-toluidine 
• 2028-84-4 p-methylbenzenediazonium chloride 
• 5873-88-1 2-Ethoxycarbonyl-S-methylthioacetamidate hydrochloride 
• 13621-50-6 ethoxycarbonylthioacetamide 
• 122380-11-4 2-Ethoxycarbonyl-N-(4-tolyl)acetamidine hydrochloride 

Downstream Products

• 272123-49-6 1-(p-methylphenyl)-4-ethoxycarbonyl-5-[(triphenylphosphoranylidene)amino]-1,2,3-triazole 
• 1160050-83-8 5-(p-tolylamino)-2H-1,2,3-triazol-4-carbohydrazide 
• 1026253-69-9 5-amino-1-p-tolyl-1H-[1,2,3]triazole-4-carboxylic acid 
• 62469-98-1 ethyl 5-anilino-1H-v-triazole-4-carboxylate 

Relevant articles and documents

Synthesis and in vitro and in silico studies of 1H- and 2H-1,2,3-triazoles as antichagasic agents

1,2,3-triazole heterocycles stand out in medicinal chemistry for having great structural diversity and bioactivities. In this study, two series of triazoles were synthesized. One was obtained by the 1,3-dipolar cycloaddition reaction between ethyl cyanoac

Triazole [5, 4-d] pyrimidone tricyclic compounds as well as preparation method and application thereof

The invention relates to triazole [5, 4-d] pyrimidone tricyclic compounds as well as a preparation method and application thereof.The triazole [5, 4-d] pyrimidone tricyclic compounds are prepared by following steps: taking different substituted anilines a

Synthesis and crystal structure of (5-methyl-3-phenyl-1h-pyrazol-1-yl)-[5- (p-tolylamino)-2h-1,2,3-triazol-4-yl]methanone

(5-Methyl-3-phenyl-1H-pyrazol-1-yl)-[5-(p-tolylamino)-2H-1,2, 3-triazol-4-yl]methanone was synthesized and characterized by 1H NMR, MS and IR spectra data. The structure of title compound was identified by X-ray diffraction. Compound, C20

NEW METHOD FOR STUDYING THE REACTIVITIES OF α-DIAZO IMINES. INVESTIGATION OF THE CYCLIZATION OF N-SUBSTITUTED 2-DIAZOACETAMIDINES TO 1,2,3-TRIAZOLES

N-Substituted diazoacetamidines were generated in the reaction of N-substituted acetamidines with benzenesulfonyl azide.It is shown that their cyclization to isomeric 1,2,3-triazole characterizes the reactivities of α-diazo imines.The synthesis of 5-amino

Studies on v-Triazoles. Part I: Synthesis of 4,9-Dihydro-9-oxo-1H-v-triazolo quinolines by cyclization of 5-arylamino-v-triazole-4-carboxylic acids with polyphosphoric acid.

The cyclization of 5-arylamino-v-triazole-4-carboxylic acids with polyphosphoric acid leads to high yields of the corresponding 4,9-dihydro-9-oxo-v-triazolo quinolines which are potent antiallergic agents.

Triazolo [4,5-b] quinolines and prophylaxis of allergic diseases with them

The invention provides novel compounds of formula (I). STR1 and pharmaceutically acceptable salts thereof wherein R1, R2, R3 and R4 which may be the same or different, represent hydrogen, halogen, lower alkyl, and lower alkoxy, or any adjacent two of R1 to R4 taken together represent an alkylene group containing from 3 to 5 carbon atoms or a 1,4-buta-1,3-dienylene group. The compounds are useful as anti-allergic agents.