72712-19-7

Basic information

• Product Name: Ethanone, 1-[2,4-bis(acetyloxy)phenyl]-
• Synonyms: 1-(2,4-diacetoxy-phenyl)-ethanone;2,4-diacetoxyacetophenone;1-(2,4-Diacetoxy-phenyl)-aethanon;2,4-dihydroxy acetophenone diacetate;Ethanone,1-[2,4-bis(acetyloxy)phenyl];2,4-Diacetoxy-acetophenon
• CAS NO: 72712-19-7
• Molecular Formula: C12H12O5
• Molecular Weight: 236.224
• Mol File: 72712-19-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 38-38.5 °C
• Boiling Point: 367.7±32.0 °C(Predicted)
• Density: 1.203±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Ethanone, 1-[2,4-bis(acetyloxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[2,4-bis(acetyloxy)phenyl]-(72712-19-7)
• EPA Substance Registry System: Ethanone, 1-[2,4-bis(acetyloxy)phenyl]-(72712-19-7)

Safety Data

• Hazardous Substances Data: 72712-19-7(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 108-46-3 recorcinol 
• 96574-20-8 1-(2,4-diacetoxyphenyl)vinyl acetate 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 

Downstream Products

• 96574-20-8 1-(2,4-diacetoxyphenyl)vinyl acetate 
• 2896-60-8 4-ethyl-1,3-benzenediol 
• 99186-47-7 4-ethyl resorcinol monoacetate 
• 127265-10-5 4-ethylresorcinol acetate 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 42059-48-3 acetic acid 4-acetyl-3-hydroxyphenyl ester 
• 6320-42-9 7-hydroxy-2-methyl-4H-chromen-4-one 
• 52751-42-5 2'-acetoxy-4'-hydroxyacetophenone 
• 108-58-7 Resorcinol diacetate 
• 79889-80-8 2-bromo-1-(2,4-diacetoxy-phenyl)-ethanone 
• 52751-46-9 3-acetyl-7-hydroxy-2-methyl-chromen-4-one 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF 4-ALKYL RESORCINOL ESTERS

A process for the preparation of one or more esters of 4-alkyl resorcinol comprising the steps of: (i) reacting resorcinol or a pre-cursor thereof with an esterifying agent which comprises at least one of an organic acid, anhydride or chloride having a maximum carbon chain length of 18, at a temperature of 10 to 250 °C; and (ii) reducing the products from step (i) at a pH of 6.5 to 7.5 in the presence of a catalyst in an alcoholic medium.

Electrostatic catalysis by ionic aggregates: Scope and limitations of Mg(ClO4)2 as acylation catalyst

Alkali and alkaline earth metal perchlorates exhibit electrostatic catalysis in the activation of anhydrides for the acylation reaction. Perchlorates with higher values of the charge-size function of the metal ion exhibit better catalytic activity following the order Mg(ClO4) 2>Ba(ClO4)2>LiClO4. Acylation of structurally diverse phenols, thiols, alcohols, and amines have been carried out with stoichiometric amounts of anhydride at room temperature under solvent free conditions in the presence of catalytic amount of Mg(ClO4) 2. Sterically hindered and electron deficient phenols are efficiently acylated. Acylation with sterically hindered anhydrides such as iso-butyric, pivalic, and benzoic anhydrides are carried out with phenols and alcohols in excellent yields. Acid-sensitive alcohols are acylated in excellent yields without any competitive side reactions.

Novel chemoselective de-esterification of esters of polyacetoxy aromatic acids by lipases

Candida cylindracea lipase (CCL) and porcine pancreatic lipase (PPL) have been used for deacetylation of peracetates of methyl and ethyl esters of six different polyphenolic acids in organic solvents. Exclusive de-esterification of the ester groups derived from the phenolic hydroxy and aliphatic acid over the ester group of the aromatic acid and aliphatic alcohol has been achieved affording the corresponding esters of phenolic acids in as high yields as 90-97%. The results have been corroborated with the mechanism of lipase action.