52751-42-5

Basic information

• Product Name: 2'-acetoxy-4'-hydroxyacetophenone
• Synonyms: 2'-acetoxy-4'-hydroxyacetophenone
• CAS NO: 52751-42-5
• Molecular Weight: 194.187
• Mol File: 52751-42-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2'-acetoxy-4'-hydroxyacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-acetoxy-4'-hydroxyacetophenone(52751-42-5)
• EPA Substance Registry System: 2'-acetoxy-4'-hydroxyacetophenone(52751-42-5)

Safety Data

• Hazardous Substances Data: 52751-42-5(Hazardous Substances Data)

Upstream product

• 108-58-7 Resorcinol diacetate 
• 64-19-7 acetic acid 
• 42059-48-3 acetic acid 4-acetyl-3-hydroxyphenyl ester 
• 108-24-7 acetic anhydride 
• 108-46-3 recorcinol 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 72712-19-7 2,4-diacetoxy acetophenone 

Downstream Products

• 2896-60-8 4-ethyl-1,3-benzenediol 
• 99186-47-7 4-ethyl resorcinol monoacetate 
• 127265-10-5 4-ethylresorcinol acetate 

Relevant articles and documents

Utilization of the inherent nucleophile for regioselective O-acylation of polyphenols via an intermolecular cooperative transesterification

A green and efficient method for regioselective O-acylation of polyphenols has been developed. The acylation can be carried out in potassium carbonate/dimethyl sulphoxide system by utilizing the ‘inherent nucleophile’ via an intermolecular cooperative transesterification under mild condition. This method shows particular advantage in regioselective acylation of polyphenols bearing 2′,4′-dihydroxyacetophenone moiety and can be extended to the synthesis of mono or multiple acetates of polyphenols without this moiety in good yields. Compared with other reported approaches, this method is endowed with atom economy and is more environment-friendly for avoiding the use of any metal-based catalysts.

PROCESS FOR THE PREPARATION OF 4-ALKYL RESORCINOL ESTERS

A process for the preparation of one or more esters of 4-alkyl resorcinol comprising the steps of: (i) reacting resorcinol or a pre-cursor thereof with an esterifying agent which comprises at least one of an organic acid, anhydride or chloride having a maximum carbon chain length of 18, at a temperature of 10 to 250 °C; and (ii) reducing the products from step (i) at a pH of 6.5 to 7.5 in the presence of a catalyst in an alcoholic medium.

Regioselective hydrolysis of polyacetoxy aromatic ketones with lipases in organic solvents

Lipases from porcine pancreas (PPL) and Candida cylindracea (CCL) have been used for deacetylation of polyacetoxy aromatic ketones in organic solvents.A systematic study has been made to establish regioselectivity, effect of the nature of solvents and role of steric bulk on hydrolysable groups.High regioselectivity and effect of nature of solvents on the rate of the reactions have been observed.