72716-32-6Relevant academic research and scientific papers
Convenient Synthesis of 10-Deazaaminopterin via a Pteridine Ylide
Piper, James R.,Montgomery, John A.
, p. 320 - 321 (1980)
10-Deazaaminopterin, a potential antitumor agent now undergoing clinical trials, has been synthesized by a new approach involving the Wittig reaction.The ylide obtained by reaction of 6-(bromomethyl)-2,4-pteridinediamine with triphenylphosphine in Me2NAc,
