Journal of Medicinal Chemistry p. 320 - 321 (1980)
Update date:2022-08-03
Topics:
Piper, James R.
Montgomery, John A.
10-Deazaaminopterin, a potential antitumor agent now undergoing clinical trials, has been synthesized by a new approach involving the Wittig reaction.The ylide obtained by reaction of 6-(bromomethyl)-2,4-pteridinediamine with triphenylphosphine in Me2NAc,
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(1899)
