727384-30-7Relevant academic research and scientific papers
Design and synthesis of 6-oxo-1,6-dihydropyridines as CDK5 inhibitors
Kaller, Matthew R.,Zhong, Wenge,Henley, Charles,Magal, Ella,Nguyen, Thomas,Powers, David,Rzasa, Robert M.,Wang, Weiya,Xiong, Xiaoling,Norman, Mark H.
, p. 6591 - 6594 (2009)
Cyclin-dependent kinase 5 (CDK5) is a serine-threonine protein kinase that plays a significant role in neuronal development. In association with p25, CDK5 abnormally phosphorylates a number of cellular targets involved in neurodegenerative disorders. Usin
