727418-77-1Relevant academic research and scientific papers
A new strategy for 2-substituted indolylalkylamines: Synthesis of 2-aryldihomotryptamines
Nenajdenko, Valentine G,Zakurdaev, Eugene P,Balenkova, Elizabeth S
, p. 8449 - 8451 (2002)
Substituted homologues of tryptamines were synthesized in one step in high yields under mild conditions. The key intermediates are arylhydrazones of 6-aminohexanones, which undergo Fischer rearrangement readily in glacial acetic acid. An easy and ready for scale-up procedure is developed and formerly unknown 2-substituted dihomotryptamines are obtained.
Synthesis and the keto-enol equilibrium of 2-acyl lactams
Nenajdenko,Gololobov,Zakurdaev,Balenkova
, p. 2473 - 2482 (2007/10/03)
Condensation of N-substituted lactams with carboxylic acid esters was studied. A wide range of substituted 2-acyl lactams with different ring sizes were synthesized. The structure of 2-acyl lactams (primarily, the ring size) was found to influence the ket
