727663-40-3Relevant academic research and scientific papers
CuCl-catalyzed one-pot synthesis of 5,6-dihydropyrazolo[1,5-c]quinazolines
Guo, Shenghai,Wang, Jiliang,Li, Yan,Fan, Xuesen
, p. 2383 - 2388 (2014/04/03)
A simple and efficient procedure for the preparation of 5,6-dihydropyrazolo[1,5-c]quinazolines via CuCl-catalyzed tandem reaction of 5-(2-bromoaryl)-1H-pyrazoles with aldehydes and aqueous ammonia under nitrogen atmosphere has been developed. The usefulne
Synthesis of pyrazolo[1,5- c ]quinazoline derivatives through copper-catalyzed tandem reaction of 5-(2-bromoaryl)-1 H -pyrazoles with carbonyl compounds and aqueous ammonia
Guo, Shenghai,Wang, Jiliang,Fan, Xuesen,Zhang, Xinying,Guo, Dongqiang
, p. 3262 - 3270 (2013/06/26)
A practical and efficient synthesis of pyrazolo[1,5-c]quinazolines and 5,6-dihydropyrazolo[1,5-c]quinazolines, including several spiro compounds, through copper-catalyzed tandem reaction of 5-(2-bromoaryl)-1H-pyrazoles with carbonyl compounds and aqueous ammonia under air has been developed. Compared with literature methods toward pyrazolo[1,5-c]quinazoline derivatives, the synthetic method reported in this paper has the advantages of readily available and inexpensive starting materials and reagents, broad scope of substrates, and mild reaction conditions.
