727726-41-2

Upstream product

• 63930-49-4 (R)-3-(benzyloxy)-2-methylpropan-1-ol 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 312-40-3 difluorodiphenylsilane 
• 727726-29-6 [(2S)-2-methyl-3-(phenylmethoxy)-1-propyl][2-(phenylmethyl)-1,3-dithian-2-yl]diphenylsilane 
• 727726-30-9 [2-(phenylmethyl)-1,3-dithian-2-yl]fluorodiphenylsilane 
• 31593-52-9 2-benzyl-1,3-dithiane 
• 74924-27-9 methyl (S)-3-benzyloxy-2-methylpropanoate 
• 72297-80-4 1-[((S)-3-iodo-2-methylpropoxy)methyl]benzene 
• 727726-39-8 [(2S)-2-methyl-3-(phenylmethoxy)-1-propyl][2-phenyl-1-oxoethyl]diphenylsilane 

Downstream Products

• 727726-43-4 2-[[1-[(2S)-2-methyl-3-(phenylmethoxy)-1-propyl]diphenylsilyl]-2-phenylethyl]-1H-isoindole-1,3(2H)-dione 
• 727726-32-1 [(2S)-2-methyl-3-hydroxy-1-propyl][(1R)-1-(benzoylamino)-2-phenylethyl]diphenylsilane 
• 727726-33-2 [(2S)-2-methyl-3-hydroxy-1-propyl][(1S)-1-(benzoylamino)-2-phenylethyl]diphenylsilane 
• 727726-52-5 (2S)-3-[[(1R)-1-(benzoylamino)-2-phenylethyl]diphenylsilyl]-2-methylpropanoic acid 
• 727726-53-6 (2S)-3-[[(1S)-1-(benzoylamino)-2-phenylethyl]diphenylsilyl]-2-methylpropanoic acid 
• 727726-28-5 (S)-1-{(S)-3-[((R)-1-benzamido-2-phenylethyl)difluoro sily-l]-2-methylpropanoyl}pyrrolidine-2-carboxylic acid 
• 727726-56-9 (S)-1-{(S)-3-[((S)-1-benzamido-2-phenylethyl)difluoro sily-l]-2-methylpropanoyl}pyrrolidine-2-carboxylic acid 
• 727726-45-6 [(2S)-2-methyl-3-(phenylmethoxy)-1-propyl][1-(benzoylamino)-2-phenylethyl]diphenylsilane 
• 727726-34-3 (2S)-1-[3-[[(1R)-1-(benzoylamino)-2-phenylethyl]diphenylsilyl]-2-methyl-1-oxopropyl]-L-proline 1,1-dimethylethyl ester 
• 727726-49-0 (2S)-1-[3-[[(1S)-1-(benzoylamino)-2-phenylethyl]diphenylsilyl]-2-methyl-1-oxopropyl]-L-proline 1,1-dimethylethyl ester 

Relevant academic research and scientific papers

Silanediol inhibitors of angiotensin-converting enzyme. Synthesis and evaluation of four diastereomers of Phe[Si]Ala dipeptide analogues

Four stereoisomers of a Phe-Ala silanediol dipeptide mimic have been evaluated as inhibitors of angiotensin-converting enzyme (ACE) and compared to ketone-based inhibitors reported by Almquist et al. One stereogenic center of the isomers was derived from

Silanediol peptidomimetics. Evaluation of four diastereomeric ACE inhibitors

Four diastereomers of a Phe-Ala peptide mimic incorporating a central silanediol group have been individually prepared and tested as inhibitors of angiotensin-converting enzyme (ACE). Three of the silanediols exhibit levels of inhibition that are similar