72297-80-4

Upstream product

• 100-39-0 benzyl bromide 
• 74924-27-9 methyl (S)-3-benzyloxy-2-methylpropanoate 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 203454-44-8 (R)-4-Benzyl-3-((S)-3-benzyloxy-2-methyl-propionyl)-oxazolidin-2-one 
• 3587-60-8 Benzyloxymethyl chloride 
• 63930-49-4 (R)-3-(benzyloxy)-2-methylpropan-1-ol 
• 86951-92-0 (2S)-3-Benzyloxy-2-methyl-1-p-(toluenesulphonyloxy)propane 

Downstream Products

• 128440-39-1 (2S,2'R,4'R)-1-(5'-(benzyloxy)-2',4'-dimethylpentanoyl)-2-(hydroxymethyl)pyrrolidine 
• 82924-17-2 N-<(2R,4R)-5-(benzyloxy)-4-methyl-2-(2-phenylethyl)pentanoyl>-L-prolinol 
• 204510-43-0 2-((S)-3-Benzyloxy-2-methyl-propyl)-[1,3]dithiane 
• 1597437-21-2 C₁₆H₂₂O₄ 
• 922523-28-2 C₁₅H₂₂O₂ 
• 922523-50-0 C₁₆H₂₁O₄SF₃ 
• 727726-29-6 [(2S)-2-methyl-3-(phenylmethoxy)-1-propyl][2-(phenylmethyl)-1,3-dithian-2-yl]diphenylsilane 
• 643036-49-1 (2S,4R)-5-Benzyloxy-2,4-dimethyl-pentanoic acid ((1R,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide 
• 126559-89-5 (S)-(-)-3-benzyloxy-2-methyl-triphenylphosphonium iodide 
• 1597437-23-4 C₂₂H₃₈O₄Si 

Relevant academic research and scientific papers

First stereoselective total synthesis and biological evaluation of amphidinin B and Its analogues

A highly stereoselective first total synthesis of amphidinin B is described. The key steps involved in this synthesis are the generation of the exo-double bond in the C1-C9 segment, the Barbier allylation, enzymatic kinetic resolutio

Synthesis of the southern FGHI ring system of azaspiracid-1 and investigation into the controlling elements of C28- and C36-ketalization

Heading south: An efficient approach to the FGHI southern ring system of azaspiracid-1 is disclosed. Each of the eight stereogenic centers is generated with excellent diastereoselectivity. In addition, the stereochemical outcome of the ketalization steps could be controlled by careful selection of the conditions. Teoc = 2-(trimethylsilyl)ethoxycarbonyl; TMS = trimethylsilyl; TIPS = triisopropylsilyl; Bn = benzyl. (Chemical Equation Presented).

Silanediol inhibitors of angiotensin-converting enzyme. Synthesis and evaluation of four diastereomers of Phe[Si]Ala dipeptide analogues

Four stereoisomers of a Phe-Ala silanediol dipeptide mimic have been evaluated as inhibitors of angiotensin-converting enzyme (ACE) and compared to ketone-based inhibitors reported by Almquist et al. One stereogenic center of the isomers was derived from

Silanediol peptidomimetics. Evaluation of four diastereomeric ACE inhibitors

Four diastereomers of a Phe-Ala peptide mimic incorporating a central silanediol group have been individually prepared and tested as inhibitors of angiotensin-converting enzyme (ACE). Three of the silanediols exhibit levels of inhibition that are similar

Total Synthesis of (+)-Carbonolide B

The macrolide (+)-carbonolide B, the aglycon of the antibiotic carbomycin B, was synthesized via a convergent sequence.A key step of the approach is the union of aldehyde 6 with stannane 7 in the presence of MgBr2*OEt2 as Lewis acid to afford the C1-C9 fr

SYNTHESIS OF MOSESIN-4, A NATURALLY OCCURING STEROID SAPONIN WITH SHARK REPELLENT ACTIVITY, AND ITS ANALOG 7-β-GALACTOSYL ETHYL CHOLATE

The first synthesis of mosesin-4 (13), a naturally occurring steroid saponin with shark repellent activity, and its analog 19, is described.They both possess a free galactose residue attached axially at the 7α position of the steroidal aglycon.Methyl chol