727991-06-2

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 871095-80-6 5-hydroxy-6-((4-methoxybenzyloxy)methyl)-2-(p-tolylthio)tetrahydro-2H-pyran-3,4-diyl dibenzoate 
• 28244-94-2 p-tolyl-2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside 
• 604-69-3 β-D-glucose pentaacetate 
• 530-27-8 D-gulopyranose 
• 727991-05-1 p-methylphenyl 2,3-di-O-benzoyl-4,6-O-p-methoxybenzylidene-1-thio-β-D-glucopyranoside 
• 582322-04-1 4-methylphenyl (S)-4,6-O-[(4-methoxyphenyl)methylene]-1-thio-β-D-glucopyranoside 
• 1152-39-2 p-methylphenyl 1-thio-β-D-glucopyranoside 

Downstream Products

• 727991-07-3 5-(tert-butyldimethylsilyloxy)-6-(hydroxymethyl)-2-(p-tolylthio)tetrahydro-2H-pyran-3,4-diyldibenzoate 
• 727991-08-4 p-methylphenyl (methyl 2,3-di-O-benzoyl-4-O-tert-butyldimethylsilyl-1-thio-β-D-glucopyranosyluronate) 
• 871095-81-7 (2S,3S,4R,5R,6S)-4,5-Bis-benzoyloxy-3-(tert-butyl-dimethyl-silanyloxy)-6-p-tolylsulfanyl-tetrahydro-pyran-2-carboxylic acid 

Relevant academic research and scientific papers

Key disaccharide repeat unit of glucuronic mannan oligosaccharide and preparation method of key disaccharide repeat unit

The invention provides a skeleton structure of a key disaccharide repeat unit of glucuronic mannan oligosaccharide and a preparation method of the skeleton structure. According to the key disacchariderepeat unit, glucose and mannose are used as raw materials, the key disaccharide repeat unit of glucuronic mannan oligosaccharide for treating or/and preventing Parkinson's disease and nephropathy isprepared through simple and easy-to-implement synthesis steps, and leaving groups of the key disaccharide repeat unit can be used as a glycosyl donor after being modified. The glucuronic acid can beused as a glycosyl receptor after four-position hydroxyl protecting groups of the glucuronic acid are removed, can be conveniently used for extending a carbohydrate chain of glucuronic mannan oligosaccharide, and has a key application value in the field of synthesis of the glucuronic mannan oligosaccharide.

An investigation of construction of chondroitin sulfate E (CS-E) repeating unit

A series of the derivatives of chondroitin sulfate E (CS-E) disaccharide repeating unit were prepared by postglycosylation–oxidation strategy. The strategy showed excellent performance in glycosylation both on the reactivity and stereoselectivity. Different protecting methodologies were used for the manipulation of disaccharide building blocks. Substitutes at C-4 of glucosyl donors mildly influenced the glycosylation. The current synthesis afforded a feasible approach for the preparation of CS-E repeating unit.

SMALL MOLECULE STIMULATORS OF NEURONAL GROWTH

Provided herein are small molecule stimulators of neuronal growth, their preparation, and their use for treatment of neurological disorders. In one embodiment, provided herein are methods of treatment, prevention, or amelioration of a variety of medical c

A chondroitin sulfate small molecule that stimulates neuronal growth

Chondroitin sulfate glycosaminoglycans are sulfated polysaccharides involved in cell division, neuronal development, and spinal cord injury. Here, we report the synthesis and identification of a chondroitin sulfate tetrasaccharide that stimulates the grow