72808-65-2

Upstream product

• 23133-37-1 1-propyl-4-piperidone 
• 1006-94-6 5-methoxylindole 
• 107-08-4 1-iodo-propane 
• 66611-26-5 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole 
• 680-31-9 N,N,N,N,N,N-hexamethylphosphoric triamide 
• 40064-34-4 piperidine-4,4-diol hydrochloride 

Relevant academic research and scientific papers

Three-dimensional quantitative structure-activity relationships of 5-HT receptor binding data for tetrahydropyridinylindole derivatives: A comparison of the Hansch and CoMFA methods

A series of new derivatives of 3-(1,2,5,6-tetrahydropyridin-4-yl)indole (4-THPI) has been synthesized, and their dissociation constants at the 5- HT(1A) and 5-HT2 serotonin (5-HT) receptor subtypes have been determined. The new data were combin

Tetrahydropyridinyl indoles

Novel tetrahydropyridinyl indoles of the formula STR1 wherein R' is selected from the group consisting of hydrogen, halogen and alkoxy of 1 to 3 carbon atoms, R1 and R2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 3 carbon atoms and X' is selected from the group consisting of alkyl of 1 to 6 carbon atoms, cycloalkyl of 4 to 7 carbon atoms, alkenyl and alkynyl of 2 to 5 carbon atoms and aralkyl of 7 to 12 carbon atoms with the proviso that when X' is methyl, at least one of R', R1 and R2 contain more than one carbon atom and when X' is benzyl, at least one of R', R1 and R2 must not be hydrogen and their non-toxic, pharmaceutically acceptable acid addition salts having antidepressive and neuroleptic properties as well as antiemetic properties.