72837-38-8Relevant articles and documents
Synthesis of N-(α-fluorovinyl)azoles by the reaction of difluoroalkenes with azoles
Xiong, Yang,Zhang, Xuxue,Huang, Tao,Cao, Song
, p. 6395 - 6402 (2014/08/05)
A mild and versatile method for the construction of C-N bonds by the reaction of (2,2-difluorovinyl)arenes with various N-H-containing heterocycles in the presence of K3PO4 has been developed. The reaction proceeded efficiently at room temperature (25 °C) affording the (E)-N-α-fluorovinyl derivatives of azoles 3 in good to excellent yields with relatively high stereoselectivity.