72850-33-0

Usage

Uses

Used in Research Applications:
Pyrido[2,3-b][1,4]benzodioxin is used as a research compound for exploring its potential biological activity and interactions with various receptors in the body. Its unique fused tricyclic ring structure makes it an interesting subject for scientific investigation, particularly in the fields of chemistry and pharmacology.
Used in Pharmaceutical Research:
In the pharmaceutical industry, Pyrido[2,3-b][1,4]benzodioxin is used as a starting material or intermediate in the synthesis of more complex molecules with potential therapeutic applications. Its structural properties may contribute to the development of new drugs, although further research is required to determine its suitability and efficacy in this context.
Used in Chemical Synthesis:
Pyrido[2,3-b][1,4]benzodioxin is used as a building block in the synthesis of other complex organic compounds. Its tricyclic structure provides a versatile platform for the attachment of various functional groups, making it a valuable component in the creation of novel chemical entities with potential applications in various industries.

Upstream product

• 2402-77-9 2,3-dichloro-pyridine 
• 120-80-9 benzene-1,2-diol 
• 1336-21-6 ammonium hydroxide 
• 72850-36-3 2-chloro-3-(2-methoxyphenoxy)pyridine 
• 52200-48-3 3-bromo-2-chloropyridine 
• 16867-04-2 dihydroxypyridine 

Relevant academic research and scientific papers

Base-regulated tunable synthesis of pyridobenzoxazepinones and pyridobenzoxazines

A base-regulated one-pot protocol for the tunable synthesis of pyridobenzoxazepinones and pyridobenzoxazines has been developed. The preparation of pyridobenzoxazepinones is achieved in moderate to good yield by utilizing an aromatic nucleophilic substitution (SNAr, O-arylation)/carbonylation tandem reaction. Mechanistic studies suggest that SNAr (O-arylation) proceeds prior to the aminocarbonylation. Through the regulation of bases, pyridobenzoxazines can be obtained via successive SNAr (O-arylation and then N-arylation). Base is crucial for the regulation of the products.

An Improved Synthesis of Substituted Dibenzodioxines

An improved general synthesis of substituted dibenzodioxines by reaction of catechol and substituted 1,2-dichloro- or 2-chloronitro-benzenes with metallic potassium in hexamethylphosphoramide is reported.The yields are generally superior to those in published methods, and in particular the reaction appears the one of choice for the synthesis of both the parent dibenzodioxine and the 1-carboxy derivative.

Synthesis of Some Heterocyclic Skeletons via Organoiron Complexes. Crystal and Molecular Structure of (5a,6,7,8,9,9a-η6-1,4-Benzoxathiinopyridine)(η5-cyclopentadienyl)iron Hexafluorophosphate

Synthesis of the heterocyclic skeletons of some biologically active compounds from (η6-dichlorobenzene)(η5-cyclopentadienyl)iron hexafluorophosphate in a two step procedure is described.Cyclopentadienyliron hexafluorophosphate complexes of 1,4-benzodioxinopyridine, 1,4-benzoxathiinopyridine, 10H-pyridobenzoxazine, benzonaphthodioxin, 4-methylbenzobenzopyran-2-onedioxin and benzoanthracen-9,10-dionodioxin were isolated and characterized.Upon pyrolytic sublimation of these complexes the free heterocycles were obtained and characterized. (η6-1,4-Benzoxathiinopyridine)(η5-cyclopentadienyl)iron hexafluorophosphate crystalizes in the orthorhombic system, space group Pbca; the dihedral angle between the planes of outerrings was found to be 176.6 (1).

New pyridobenzodioxin compounds and methods for their production

Pyridobenzodioxin compounds, which are useful as pharmacological agents, especially as agents for the treatment of senility and reversal of amnesia, and methods for their preparation are disclosed. Pharmaceutical compositions containing said compounds and methods for using said compositions in treating senility and reversal of amnesia are also taught.