72904-38-2Relevant academic research and scientific papers
Graphite catalyzed green synthesis of quinoxalines
Kadam, Hari K.,Khan, Salman,Kunkalkar, Rupesh A.,Tilve, Santosh G.
, p. 1003 - 1007 (2013/02/25)
A new simple approach using environmentally benign, cheap, and easily recyclable graphite as a heterogeneous catalyst for the synthesis of quinoxalines is described. A library of pharmacologically interesting diphenylquinoxalines is prepared by the double condensation of substituted benzils, phenanthrene-9,10-dione, and benzoin with aromatic diamines in 71-93% yields at room temperature in ethanol. Aliphatic diamines gave corresponding dihydropyrazines from substituted benzils in 72-92% yields.
YbCl3-catalyzed one-pot synthesis of dihydropyrazines, piperazines, and pyrazines
Fan, Liyan,Chen, Wen,Qian, Changtao
supporting information, p. 231 - 234 (2013/02/23)
A simple and efficient synthetic approach to dihydropyrazines via YbCl 3-catalyzed reaction of α-hydroxyketones with diamines under mild conditions was developed. The corresponding 2,3-subsitituted piperazines and pyrazines were obtained through tandem conversion of dihydropyrazines with good yields.
Microwave-assisted synthesis of quinoxalines in peg-400
Zhang, Xia-Zhong,Wang, Jin-Xian,Bai, Lin
experimental part, p. 2053 - 2063 (2011/07/07)
A rapid and efficient procedure for the synthesis of quinoxaline derivatives has been achieved by condensation of aryl-1,2-diamines with 1,2-dicarbonyl compounds catalyzed by polyethylene glycol under CEM-focused microwave-irradiation conditions. Copyright
