72944-04-8Relevant academic research and scientific papers
Palladium-Catalyzed Directed para C?H Functionalization of Phenols
Patra, Tuhin,Bag, Sukdev,Kancherla, Rajesh,Mondal, Anirban,Dey, Aniruddha,Pimparkar, Sandeep,Agasti, Soumitra,Modak, Atanu,Maiti, Debabrata
supporting information, p. 7751 - 7755 (2016/07/07)
Various practical methods for the selective C?H functionalization of the ortho and recently also of the meta position of an arene have already been developed. Following our recent development of the directing-group-assisted para C?H functionalization of toluene derivatives, we herein report the first remote para C?H functionalization of phenol derivatives by using a recyclable silicon-containing biphenyl-based template. The effectiveness of this strategy was illustrated with different synthetic elaborations and by the synthesis of various phenol-based natural products.
First total synthesis of artepillin C established by o,o′-diprenylation of p-halophenols in water
Uto, Yoshihiro,Hirata, Akihiko,Fujita, Tomoya,Takubo, Syunsuke,Nagasawa, Hideko,Hori, Hitoshi
, p. 2355 - 2357 (2007/10/03)
We have demonstrated that prenylation of phalophenols was dependent on the solvent effect and succeeded in o,o′-diprenylation of p-halophenols in water. Following the Mizoroki-Heck coupling of the diprenyl-piodophenol 3c with methyl acrylate and then hydr
PHENOL DERIVATIVES, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF
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Page column 14, (2010/01/31)
Disclosed are an efficient, safe process for producing artepillin C and derivatives thereof by an organic synthesis. The process comprises a step of reacting a phenol derivative with an acrylate or acrylic acid.
