72984-63-5

Upstream product

• 58719-77-0 2-O-benzyl-D-glucopyranose 
• 108-24-7 acetic anhydride 
• 7177-79-9 methyl 2,3-O-dibenzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 53958-32-0 methyl α-D-glucopyranoside 2-benzyl ether 
• 55287-62-2 O²-benzyl-O³,O⁴-isopropyliden-1,6-anhydro-β-D-galactopyranose 
• 52579-97-2 1,6-anhydro-3,4-O-isopropylidene-β-D-galactopyranose 
• 100-39-0 benzyl bromide 
• 127753-57-5 allyl-3-O-allyl-4,6-O-benzylidene-D-glucopyranoside 
• 37111-84-5 allyl-3-O-allyl-2-O-benzyl-4,6-O-benzylidene-D-glucopyranoside 
• 15038-71-8 methyl 2-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 55735-75-6 methyl 3,4,6-tri-O-acetyl-2-O-benzyl-α-D-glucopyranoside 

Downstream Products

• 219864-81-0 Acetic acid (2R,3R,4S,5R,6R)-3-acetoxy-2-acetoxymethyl-5,6-bis-benzyloxy-tetrahydro-pyran-4-yl ester 
• 127753-60-0 (E)(prop-2-enal)-3-yl 2-O-benzyl-3,4,6-tri-O-acetyl-β-D-glucopyranoside 
• 106680-71-1 (2R,3S,4S,5R,6R)-2-Hydroxymethyl-6-(2-hydroxymethyl-2-methyl-cyclohexyloxy)-tetrahydro-pyran-3,4,5-triol 
• 106680-71-1 (2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-(2-hydroxymethyl-2-methyl-cyclohexyloxy)-tetrahydro-pyran-3,4,5-triol 
• 127753-63-3 (2R,3S,4S,5R,6R)-5-Benzyloxy-6-[((E)-buta-1,3-dienyl)oxy]-2-hydroxymethyl-tetrahydro-pyran-3,4-diol 
• 127753-64-4 (2R,3S,4S,5R,6S)-5-Benzyloxy-6-[((E)-buta-1,3-dienyl)oxy]-2-hydroxymethyl-tetrahydro-pyran-3,4-diol 
• 127753-61-1 (E)buta-1,3-dienyl 2-O-benzyl-3,4,6-tri-O-acetyl-β-D-glucopyranoside 
• 127753-62-2 (E)buta-1,3-dienyl 2-O-benzyl-3,4,6-tri-O-acetyl-α-D-glucopyranoside 
• 79705-36-5 Benzyl-2,3-O-isopropyliden-4-O-(3,4,6-tri-O-acetyl-2-O-benzyl-α-D-galactopyranosyl)-α-L-rhamnopyranosid 
• 79705-41-2 Benzyl-4-O-(3,4,6-tri-O-acetyl-2-O-benzyl-α-D-galactopyranosyl)-α-L-rhamnopyranosid 
• 79705-33-2 (2,2,2-Trichlorethyl)-2,3-O-isopropyliden-4-O-(3,4,6-tri-O-acetyl-2-O-benzyl-α-D-galactopyranosyl)-α-L-rhamnopyranosid 
• 79705-42-3 Benzyl-4-0-(2-O-benzyl-α-D-galactopyranosyl)-α-L-rhamnopyranosid 
• 55287-66-6 Acetic acid (2R,3S,4S,5R,6S)-4-acetoxy-2-acetoxymethyl-5-benzyloxy-6-chloro-tetrahydro-pyran-3-yl ester 
• 791611-43-3 Acetic acid (2R,3S,4S,5R,6S)-3-acetoxy-2-acetoxymethyl-5-benzyloxy-6-((2S,3S,4R)-3,4-diacetoxy-2-tetracosanoylamino-tridecyloxy)-tetrahydro-pyran-4-yl ester 

Relevant academic research and scientific papers

Facile and regioselective preparation of partly O-benzylated d-glucopyranose acetates via acid-mediated simultaneous debenzylation-acetolysis

Fully O-benzylated methyl α-d-glucopyranoside shows a steady order in stepwise debenzylation when it is treated with sulfuric acid in acetic anhydride. Based on the order of debenzylation, regioselective preparations of 2,3,4-tri-, 2,3-, 2,4-, 3,4-di-, an

Effects of lipid chain lengths in α-galactosylceramides on cytokine release by natural killer T cells

Glycolipid presentation by CD1 proteins has emerged as an important aspect of antigen recognition, and presentation of α-glycosylceramides by CD1d to natural killer T cells has become a central focus in understanding how glycolipid presentation can influence immune responses. An α-galactosylceramide containing relatively long lipid chains has been the subject of intense study because, when presented by CD1d to natural killer T cells, it stimulates the release of both proinflammatory and immunomodulatory cytokines. Using an efficient synthesis of α-galactosylceramides, we have prepared a series of glycolipids in which the lipid chain lengths have been incrementally varied. The responses of natural killer T cells to these glycolipids have been determined, and we have found that truncation of the phytosphingosine lipid chain increases the relative amounts of immunomodulatory cytokines released. In similar fashion, the length of the acyl chain in α-galactosylceramides influences cytokine release profiles. Copyright

Chemical Synthesis of Disaccharides which are Partial Structures of the Glycosaminoglycan Heparan Sulfate

A specific tetradecasaccharide sequence (oligo-H, 1) of the proteoglycan heparan sulfate has recently been identified as being responsible for binding and activation of the basic fibroplast growth factor (bFGF), a potent mitogen.We present here the first

STEREOCHEMICAL VARIATIONS IN AQUEOUS CYCLOADDITIONS USING GLYCO-ORGANIC SUBSTRATES AS A CONSEQUENCE OF CHEMICAL MANIPULATIONS ON THE SUGAR MOIETY

Chemical modifications of the sugar moiety in dienyl glycosides allowed us to rationalize the stereochemistry of our aqueous cycloadditions using glyco-organic substrates.In this way, several dienyl glucosides having benzyl group in 2 or 6 position of the